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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

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911399

Sigma-Aldrich

聚(乙二醇)甲醚-嵌段-聚(丙交酯-co-乙交酯)

PEG average Mn 2,000, PLGA average Mn 10,000, lactide:glycolide 80:20

别名:

PEG-PLGA, PEG2K-PLGA10K, mPEG-b-PLGA

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选择尺寸

0.2 MG
¥2,217.29
0.5 MG
¥3,324.19
5 X .2 MG
¥6,970.62

¥2,217.29

国内现货，预计发货时间2025年4月14日详情

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0.2 MG
¥2,217.29
0.5 MG
¥3,324.19
5 X .2 MG
¥6,970.62

About This Item

线性分子式:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
UNSPSC代码:
12352112
NACRES:
NA.23

¥2,217.29

国内现货，预计发货时间2025年4月14日详情

获取大包装报价

质量水平

100

表单

powder or chunks

投料比

lactide:glycolide 80:20

分子量

PEG average Mn 2,000 (by NMR)
PLGA average Mn 10,000 (by NMR)

颜色

off-white to faint brown

储存温度

−20°C

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H1404SRP3027E4127
hEGF EGF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

E9644

hEGF

Hepatocyte Growth Factor human HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture

H1404

Hepatocyte Growth Factor human

EGF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

SRP3027

EGF human

Epidermal Growth Factor from murine submaxillary gland EGF, suitable for cell culture

E4127

Epidermal Growth Factor from murine submaxillary gland

recombinant

expressed in E. coli

recombinant

expressed in Baculovirus infected High-5 cells

recombinant

expressed in E. coli

recombinant

-

assay

≥97% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

assay

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

Quality Level

300

Quality Level

200

Quality Level

-

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized

form

lyophilized powder

应用

This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    MKCW3552
    MKCL4635

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    Fabienne Danhier et al.
    Journal of controlled release : official journal of the Controlled Release Society, 133(1), 11-17 (2008-10-28)
    The purpose of this study was to develop Cremophor EL-free nanoparticles loaded with Paclitaxel (PTX), intended to be intravenously administered, able to improve the therapeutic index of the drug and devoid of the adverse effects of Cremophor EL. PTX-loaded PEGylated
    Miles A Miller et al.
    Nature communications, 6, 8692-8692 (2015-10-28)
    Therapeutic nanoparticles (TNPs) aim to deliver drugs more safely and effectively to cancers, yet clinical results have been unpredictable owing to limited in vivo understanding. Here we use single-cell imaging of intratumoral TNP pharmacokinetics and pharmacodynamics to better comprehend their
    Yihan Xu et al.
    Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
    Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
    R Gref et al.
    Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
    Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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