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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
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主要文件

909904

Sigma-Aldrich

4arm-poly(lactide-co-glycolide)

average Mn 38,000-60,000, lactide:glycolide 55:45

别名:

4 arm PLGA, 4 arm-PLGA, 4arm-PLGA

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500 MG
¥1,078.83

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500 MG
¥1,078.83

About This Item

线性分子式:
C5H8O4((((C3H4O2)x(C2H2O2)y)m)H)4
UNSPSC代码:
12162002
NACRES:
NA.23

¥1,078.83


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表单

powder or chunks

投料比

lactide:glycolide 55:45

分子量

average Mn 38,000-60,000

颜色

white to tan

储存温度

−20°C

应用

Biocompatible and biodegradable polymer. Can be used in the formation of nanoparticles for drug delivery. The multi-arm molecular structure might promote high drug loading, superior colloidal stability, as well as long circulation time.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Xiuxiu Wang et al.
    Biomacromolecules, 19(4), 1368-1373 (2018-03-20)
    PLGA, a copolymer of lactide and glycolide, is one of the most used biodegradable polymers that find a wide range of biomedical applications including drug delivery and tissue engineering. However, in spite of remarkable advancement, nanotherapeutics based on PLGA might
    R Gref et al.
    Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
    Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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    Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

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