909874
N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide)
PEG average Mn 5,000, PDLA average Mn 16,000
别名:
NHS ester PEG-PDLA, NHS ester PEG-PLA, NHS-PEG-PDLA, NHS-PEG-PLA
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2.5 KG
¥1,336.16
5 KG
¥1,666.70
About This Item
线性分子式:
HO(C3H4O2)m(C2H4O)nC7H8NO4
UNSPSC代码:
12352005
NACRES:
NA.23
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表单
powder or chunks
分子量
PDLA average Mn 16,000 (by NMR)
PEG average Mn 5,000 (by NMR)
颜色
white to tan
储存温度
−20°C
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1 of 4
此商品 | 529600 | C7594 | B6429 |
|---|---|---|---|
| form liquid | form liquid | form powder blend | form solution |
| storage condition OK to freeze | storage condition OK to freeze | storage condition - | storage condition - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp | storage temp. room temp |
| shipped in ambient | shipped in ambient | shipped in - | shipped in - |
| manufacturer/tradename Novagen® | manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - |
应用
N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The NHS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ahmet Kertmen et al.
Langmuir : the ACS journal of surfaces and colloids, 35(15), 5281-5293 (2019-03-27)
Numerous glutamine analogues have been reported as irreversible inhibitors of the glucosamine-6-phosphate (GlcN-6-P) synthase in pathogenic Candida albicans in the last 3.5 decades. Among the reported inhibitors, the most effective N3-(4-methoxyfumaroyl)-l-2,3-diaminopropanoic acid (FMDP) has been extensively studied in order to
Ren Zhong Xiao et al.
International journal of nanomedicine, 5, 1057-1065 (2010-12-21)
Due to their small particle size and large and modifiable surface, nanoparticles have unique advantages compared with other drug carriers. As a research focus in recent years, polyethylene glycol-polylactic acid (PEG-PLA) block copolymer and its end-group derivative nanoparticles can enhance
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these
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Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.
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