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Merck
CN

908886

Sigma-Aldrich

N-Cyano-4-methoxy-picolinimidamide

≥95%

别名:

Weix ligand

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About This Item

经验公式(希尔记法):
C8H8N4O
分子量:
176.18
MDL编号:
UNSPSC代码:
12352111
NACRES:
NA.22

方案

≥95%

表单

powder or crystals

反应适用性

reagent type: catalyst
reaction type: Cross Couplings

mp

220-225 °C

SMILES字符串

N(C(=N)c1nccc(c1)OC)C#N

InChI

1S/C8H8N4O/c1-13-6-2-3-11-7(4-6)8(10)12-5-9/h2-4H,1H3,(H2,10,12)

InChI key

LEWHOCRDELQPCV-UHFFFAOYSA-N

应用

This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix′s lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Eric C Hansen et al.
Nature chemistry, 8(12), 1126-1130 (2016-11-23)
Ligands are essential for controlling the reactivity and selectivity of reactions catalysed by transition metals. Access to large phosphine ligand libraries has become an essential tool for the application of metal-catalysed reactions industrially, but these existing libraries are not well

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