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Merck
CN

908533

Sigma-Aldrich

Poly(D,L-lactide-b-glycolide) lactide:glycolide 50:50

diamine, viscosity 0.035 dL/g 

别名:

Amino-functionalized PLGA, NH2-PLGA-NH2, PLGA diamine

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About This Item

线性分子式:
C6H11N4O3(C2H2O2)y-1(C3H4O2)xC4H4O4(C3H4O2)x(C2H2O2)y-1C6H11N4O3
UNSPSC代码:
12162002
NACRES:
NA.23

表单

powder or chunks

投料比

lactide:glycolide 50:50

颜色

white to tan

粘度

0.035 dL/g

储存温度

−20°C

应用

Biocompatible and biodegradable polymer can be used in the formation of nanoparticles for drug delivery. The amine functional groups on both chain ends enable rapid and facile surface functionalization, allowing for this material to be used in applications such as targeted drug delivery.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

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