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别名:
(S)-5-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, (S)-5-Fmoc-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block
经验公式（希尔记法）:
C20H17N3O4
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检测方案
≥95%
形式
powder
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
mp
113-116 °C
应用
peptide synthesis
官能团
Fmoc
储存温度
−20°C
应用
Fmoc-L-photo-proline is a diazirine-containing, Fmoc-protected proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907286.
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
其他说明
Chemical Probes Unravel an Antimicrobial Defense Response Triggered by Binding of the Human Opioid Dynorphin to a Bacterial Sensor Kinase
Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
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说明
价格
警示用语：
Danger
危险声明
危险分类
Self-react. C
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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