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Merck
CN
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文件

安全信息

906840

Sigma-Aldrich

聚(L-丙交酯-co-己内酯)

lactide:caprolactone 90:10, viscosity 1.7 dL/g 

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别名:
PCL-PLLA, PLLA-PCL
线性分子式:
CH3(C6H10O2)m(C6H8O4)nCH3
UNSPSC代码:
12162002

形式

chunks

投料比

lactide:caprolactone 90:10

颜色

white to off-white

粘度

1.7 dL/g

储存温度

−20°C

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一般描述

Poly(L-lactide-co-caprolactone) (PCL-PLLA) is a biodegradable polymer which can be synthesized by bulk ring-opening copolymerization of L-lactide and ε-caprolactone. Its properties include flexibility, biocompatibility and controlled degradation process.

应用

PCL-PLLA can be used for a variety of applications such as tissue engineering, bone fixation devices and surgical sutures.
Poly(L-lactide-co-caprolactone) (PLLA-PCL) is a biodegradable copolymer. poly(L-lactide) exhibits a high modulus and has been often copolymerized with PCL to improve the mechanical properties of PCL, and increase degradation rate of the resulting polymer. PLLA-PCL has been used in tissue engineering, 3D bioprinting and drug delivery research applications.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Application of a bilayer tubular scaffold based on electrospun poly (L-lactide-co-caprolactone)/collagen fibers and yarns for tracheal tissue engineering
Wu T, et al.
Journal of materials chemistry. B, 5(1), 139-150 (2017)
Preparation of a poly (L-lactide-co-caprolactone) copolymer using a novel tin (II) alkoxide initiator and its fiber processing for potential use as an absorbable monofilament surgical suture
Ruengdechawiwat S, et al.
International Journal of Polymeric Materials and Polymeric Biomaterials, 65(6), 277-284 (2016)
Preclinical animal study and human clinical trial data of co-electrospun poly (L-lactide-co-caprolactone) and fibrinogen mesh for anterior pelvic floor reconstruction
Wu X, et al.
International journal of nanomedicine, 11(6), 389-389 (2016)
Comparison of plasma and chemical modifications of poly-L-lactide-co-caprolactone scaffolds for heparin conjugation
Hsieh Y, et al.
Bio-medical materials and engineering, 12(6), 065004-065004 (2017)
Fabrication and characterization of vitamin B5 loaded poly (l-lactide-co-caprolactone)/silk fiber aligned electrospun nanofibers for schwann cell proliferation
Bhutto MA, et al.
Colloids and Surfaces. B, Biointerfaces, 144(6), 108-117 (2016)

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