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Merck
CN

901330

Sigma-Aldrich

Bis-MPA-NHBoc dendrimer

trimethylol propane core, generation 2

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别名:
Bis-MPA dendrimer, NHBoc functionalized dendrimer, PFD-G2-TMP-NH-BOC
经验公式(希尔记法):
C147H242N12O66
分子量:
3233.54
UNSPSC代码:
12352200
NACRES:
NA.23

形式

solid or viscous liquid

分子量

generation 2

表面基团编号

12

颜色

colorless to pale yellow

储存温度

−20°C

一般描述

  • Polymer architecture: Dendrimer
  • Generation: 2
  • End Group Functionality: Boc-protected amine
  • No. Surface Groups: 12
  • Calculated Mol. Wt.: 3233.57 g/mol
  • Boc : tert-Butyloxycarbonyl
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.

应用

Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrimers synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrimers can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

商品

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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