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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
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主要文件

900949

Sigma-Aldrich

聚(乙二醇)甲醚-嵌段-聚(丙交酯-co-乙交酯)

PEG average Mn 5,000, PLGA Mn 20,000, lactide:glycolide 50:50

别名:

PEG-PLGA, mPEG-b-PLGA

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50 ML
CN¥3,007.68

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50 ML
CN¥3,007.68

About This Item

线性分子式:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
UNSPSC代码:
12352112
NACRES:
NA.23

CN¥3,007.68


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表单

crystals

质量水平

投料比

lactide:glycolide 50:50

分子量

PEG average Mn 5,000
PLGA Mn 20,000

运输

dry ice

储存温度

−20°C

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此商品
C9249C6295C1556
sterility

sterile-filtered

sterility

-

sterility

sterile-filtered

sterility

sterile-filtered

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

cell culture | mammalian: suitable, cryopreservation: suitable

technique(s)

cell culture | mammalian: suitable, cryopreservation: suitable

technique(s)

cell culture | mammalian: suitable, cryopreservation: suitable

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

shipped in

ambient

shipped in

wet ice

shipped in

dry ice

shipped in

ambient

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

一般描述

通过 GC 分析含有 ≤500 ppm 杂质,包括痕量单体和残留有机物。

应用

生物相容性的嵌段共聚物。可用于形成用于药物递送的纳米颗粒。具有用于癌症药物、抗炎药、抗生素或麻醉剂的靶向或受控释放的潜力。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Fabienne Danhier et al.
    Journal of controlled release : official journal of the Controlled Release Society, 133(1), 11-17 (2008-10-28)
    The purpose of this study was to develop Cremophor EL-free nanoparticles loaded with Paclitaxel (PTX), intended to be intravenously administered, able to improve the therapeutic index of the drug and devoid of the adverse effects of Cremophor EL. PTX-loaded PEGylated
    Miles A Miller et al.
    Nature communications, 6, 8692-8692 (2015-10-28)
    Therapeutic nanoparticles (TNPs) aim to deliver drugs more safely and effectively to cancers, yet clinical results have been unpredictable owing to limited in vivo understanding. Here we use single-cell imaging of intratumoral TNP pharmacokinetics and pharmacodynamics to better comprehend their
    Yihan Xu et al.
    Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
    Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
    R Gref et al.
    Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
    Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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