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Merck
CN

900914

Sigma-Aldrich

Methyltetrazine-NHS ester

≥95%

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别名:
2,5-Dioxo-1-pyrrolidinyl 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetate
经验公式(希尔记法):
C15H13N5O4
分子量:
327.29
MDL编号:
UNSPSC代码:
12352108
NACRES:
NA.22

质量水平

检测方案

≥95%

形式

powder or crystals

反应适用性

reaction type: click chemistry
reagent type: cross-linking reagent

官能团

NHS ester

储存温度

−20°C

SMILES字符串

O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3

应用

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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