900653
Poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε-caprolactone)
5k-10k-5k
别名:
PCL-PEG-PCL, PCL-PEG-PCL triblock copolymer
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关于此项目
线性分子式:
H(OCH2CH2CH2CH2CH2CO)mO(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
NACRES:
NA.23
UNSPSC Code:
12162002
产品名称
Poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε-caprolactone), 5k-10k-5k
form
powder or chunks
transition temp
flash point >230 °F
Tm 52-59 °C
storage temp.
2-8°C
Quality Level
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Application
Biocompatible, amphiphilic triblock polymer composed of a hydrophilic, central PEG block and two terminal hydrophobic PCL blocks. These materials have been used in drug delivery applications as well as thermoplastic elastomers. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Poly(caprolactone)-poly(ethylene glycol)-poly(caprolactone) (PCL-PEG-PCL) nanoparticles: a valuable and efficient system for in vitro and in vivo delivery of curcumin.
Manjii HK, et al.
Royal Society of Chemistry Advances, 6(17), 14403-14415 (2016)
Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films.
You JH, et al.
Macromolecular Research, 16(7), 609-613 (2008)
ChangYang Gong et al.
International journal of pharmaceutics, 365(1-2), 89-99 (2008-09-17)
In this work, a series of biodegradable triblock poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG, PECE) copolymers were successfully synthesized by ring-opening copolymerization, and were characterized by (1)H NMR, FT-IR, GPC, and DSC. Aqueous solutions of PECE copolymers underwent thermosensitive sol-gel-sol transition as
Synthesis and Characterization of PEG-PCL-PEG Triblock Copolymers as Carriers of Doxorubicin for the Treatment of Breast Cancer.
Cuong NV, et al.
Journal of Applied Polymer Science, 117, 3694-3703 (2010)
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