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应用
明胶-甲基丙烯酸酯可用于形成用于组织工程和 3D 打印的交联水凝胶。它已用于内皮细胞形态形成、心肌细胞、表皮组织、可注射组织构建物、骨分化和软骨再生。研究人员已在药物递送应用中探索了微球和水凝胶形式的明胶-甲基丙烯酸酯。
WGK
WGK 3
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闪点(°C)
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法规信息
明胶类产品
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as
Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal control over material properties. In this study protein-based photodegradable hydrogels
Chaenyung Cha et al.
Biomacromolecules, 15(1), 283-290 (2013-12-19)
Microfabrication technology provides a highly versatile platform for engineering hydrogels used in biomedical applications with high-resolution control and injectability. Herein, we present a strategy of microfluidics-assisted fabrication photo-cross-linkable gelatin microgels, coupled with providing protective silica hydrogel layer on the microgel
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Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.
Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.
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