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质量水平
方案
95%
表单
powder
mp
206 °C
储存温度
−20°C
SMILES字符串
OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O1
InChI
1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
InChI key
CDEURGJCGCHYFH-DJLDLDEBSA-N
一般描述
5-乙炔基-2′-脱氧尿苷（EdU）是一种胸苷类似物，可掺入到细胞DNA中，以进行细胞增殖研究。所掺入的核苷类似物可以通过与荧光叠氮化物的铜催化点击反应来检测。
应用
5-乙炔基-2′-脱氧尿苷（EdU）用于：
有关Baseclick试剂盒的列表，参见：Baseclick试剂盒
- 在复制过程中标记新合成的DNA
- 细胞增殖试验研究
- 细胞周期分析
有关Baseclick试剂盒的列表，参见：Baseclick试剂盒
警示用语：
Danger
危险声明
危险分类
Muta. 1B - Repr. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
5-Ethynyl-2?-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells
D Qu, et.al.
Analytical Biochemistry, 417, 112-121 (2011)
Evaluation of 5-ethynyl-2?-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system
C Zeng, et.al.
Brain Research, 1319, 21-32 (2010)
Synthesis, susceptibility to enzymatic phosphorylation, cytotoxicity and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates.
Bialek-Pietras M, et al.
Journal of Organometallic Chemistry, 865, 166-172 (2018)
Cell type specific applicability of 5-ethynyl-2?-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry
S Diermeier
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 75, 535-546 (2009)
Click chemistry as a reliable method for the high-density postsynthetic functionalization of alkyne-modified DNA.
Gierlich J, et al.
Organic Letters, 8(17), 3639-3642 (2006)
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