所有图片(3)

主要文件

COO原产地证书/COA分析证书

查看所有文档

900285

MCAT-53^™

Name: MCAT-53<SUP>™</SUP>
Brand: ALDRICH

别名:

Ru₂Cl₂(p-cymene) (HCOO)₂ • HCOONa, Ru₂Cl₂(p-cymene) (HCOO)₃Na, Sodium η-6-p-cymene dichloro diruthenium (II, III) triformato complex

登录查看公司和协议定价

所有图片(3)

About This Item

经验公式（希尔记法）:

C₁₃H₁₇Cl₂NaO₆Ru₂

分子量:

565.31

UNSPSC代码:

12161600

PubChem化学物质编号:

329769798

NACRES:

NA.22

推荐产品

Slide 1 of 10

1 of 10

Sigma-Aldrich

676004

(R)-(+)-2,2′,6,6′-四甲氧基-4,4′-双(二(3,5-二甲苯基)膦-3,3′-联吡啶

Sigma-Aldrich

341568

二氯苯基钌(II)二聚体

Sigma-Aldrich

700770

(R)-SIPHOS-PE

Sigma-Aldrich

675806

(R)-(+)-2,2′,6,6′-四甲氧基-4,4′-双(二苯基膦)-3,3′-联吡啶

Sigma-Aldrich

649066

氯双环戊基膦

Sigma-Aldrich

692980

(S)-DTBM-SEGPHOS^®

Sigma-Aldrich

510807

双(环戊二烯)二氢化钨(IV)

Sigma-Aldrich

710660

(11bS)-4,5-二氢-3H-二萘并[2,1-c:1′,2′-e]磷杂庚英

Sigma-Aldrich

483656

双(环戊二烯基)二甲基锆(IV)

Sigma-Aldrich

674745

(R)-(–)-3,3′-双(三苯甲硅烷基)-1,1′-联萘-2,2′-二酚磷酸酯

表单

powder

反应适用性

core: ruthenium
reaction type: Cross Couplings
reagent type: catalyst
reaction type: C-H Activation

环保替代产品特性

Less Hazardous Chemical Syntheses
Designing Safer Chemicals
Catalysis
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

247.8 °C

环保替代产品分类

, Aligned

储存温度

2-8°C

SMILES字符串

C[Ru]OC([H])=O.[Ru]OC([H])=O.ClC.CC.CC1=CC=C(C(C)C)C=C1.COC([H])=O.Cl.[Na]

InChI

1S/C10H14.3CH2O2.2ClH.Na.2Ru.H/c1-8(2)10-6-4-9(3)5-7-10;3*2-1-3;;;;;;/h4-8H,1-3H3;3*1H,(H,2,3);2*1H;;;;/q;;;;;;;+2;+3;/p-5

InChI key

QVXXTDGUSONXKR-UHFFFAOYSA-I

一般描述

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

应用

MCAT-53 is a recyclable ruthenium-containing catalyst for C–C coupling reactions in aqueous conditions. In contrast to Pd-catalyzed reactions, MCAT-53 achieves C–H-activated C–C coupling in water under ligand-free conditions, requiring no co-solvent, surfactant, or additional steps for activation. Bench- and air-stable, MCAT-53 will find wide utility in cost-effective and greener alternatives in pharmaceutical and manufacturing processes. This water-friendly catalyst is offered in collaboration with Chicago Discovery Solutions.
The catalyst has been successfully employed to synthesize a key intermediate of anacetrapib as a single regioisomer.

其他说明

Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond Activation

MCAT-53^™: A Green Ruthenium Catalyst for Cross-Coupling & C–H Activation

法律信息

MCAT-53 is a trademark of Chicago Discovery Solutions LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

MKBZ5485V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Ruthenium (II)-catalyzed C-H bond activation and functionalization.

Arockiam PB, et al.

Chemical Reviews, 112(11), 5879-5918 (2012)

Palladium (II)-catalyzed C- H activation/C-C cross-coupling reactions: versatility and practicality.

Chen X, et al.

Angewandte Chemie (International Edition in English), 48(28), 5094-5115 (2009)

Arene Ruthenium Catalyst MCAT-53 for the Synthesis of Hetero-biaryl Compounds in Water through Aromatic C-H bond Activation.

Mehta A, et al.

Organic Process Research & Development, 22(9), 1119-1130 (2018)

Greener solvents for ruthenium and palladium-catalysed aromatic C-H bond functionalisation.

Fischmeister C & Doucet H.

Green Chemistry, 13(4), 741-753 (2011)

Key green chemistry research areas-a perspective from pharmaceutical manufacturers.

Constable DJ, et al.

Green Chemistry, 9(5), 411-420 (2017)

商品

MCAT- 53™ Catalyst for Ruthenium Formation

A recyclable, ligand-free ruthenium catalyst for C–H activation reactions and concomitant C–C bond formation in the presence of water.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

主要文件