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应用
Regenerez®聚(癸二酸甘油酯)是一种可生物吸收的弹性体。通过将PGS固化至所需的交联水平，可将其物理性能从弹性调至热固性（美国专利号9.359,472）。 PGS固有的弹性性能可用于多种再生医学和组织工程应用。
特点和优势
- 可生物吸收。
- 由天然代谢物（甘油和癸二酸）组成。
- 可调的机械性能。
- 多功能平台，可进行进一步修改。
- 近似模拟人体组织的模量。
- 在无有害免疫反应的情况下促进愈合。
法律信息
美国专利号9,359,472。
Regenerez is a registered trademark of The Secant Group, LLC
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Samer H Zaky et al.
Biomedical materials (Bristol, England), 9(2), 025003-025003 (2014-02-04)
For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. In this study, we investigated poly (glycerol sebacate) (PGS), an elastomer known primarily for its soft tissue regeneration ability, as a suitable substrate to support osteo-precursor
Wei Wu et al.
Nature medicine, 18(7), 1148-1153 (2012-06-26)
Host remodeling is important for the success of medical implants, including vascular substitutes. Synthetic and tissue-engineered grafts have yet to show clinical effectiveness in arteries smaller than 5 mm in diameter. We designed cell-free biodegradable elastomeric grafts that degrade rapidly
Qi-Zhi Chen et al.
Journal of the mechanical behavior of biomedical materials, 4(8), 1805-1818 (2011-11-22)
Poly (glycerol sebacate) (PGS) is a promising elastomer for use in soft tissue engineering. However, it is difficult to achieve with PGS a satisfactory balance of mechanical compliance and degradation rate that meet the requirements of soft tissue engineering. In
Coral Salvo-Comino et al.
Sensors (Basel, Switzerland), 21(3) (2021-02-13)
The integration of nanomaterials as electron mediators in electrochemical biosensors is taking on an essential role. Due to their high surface-to-volume ratio and high conductivity, metallic nanowires are an interesting option. In this paper, silver nanowires (AgNWs) were exploited to
Cathryn A Sundback et al.
Biomaterials, 26(27), 5454-5464 (2005-04-30)
No satisfactory method currently exists for bridging neural defects. Autografts lead to inadequate functional recovery, and most available artificial neural conduits possess unfavorable swelling and pro-inflammatory characteristics. This study examined the biocompatibility of a novel biodegradable elastomer, poly(glycerol sebacate) (PGS)
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