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Merck
CN

89377

Sigma-Aldrich

4-氟-DL-谷氨酸

≥93%

别名:

(±)-2-氨基-4-氟戊二酸

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About This Item

经验公式(希尔记法):
C5H8FNO4
CAS号:
分子量:
165.12
Beilstein:
5254612
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

质量水平

方案

≥93%

表单

solid

应用

peptide synthesis

SMILES字符串

NC(CC(F)C(O)=O)C(O)=O

InChI

1S/C5H8FNO4/c6-2(4(8)9)1-3(7)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)

InChI key

JPSHPWJJSVEEAX-UHFFFAOYSA-N

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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Stereoisomers of 4-fluoroglutamic acid: influence on Escherichia coli glutamate decarboxylase.
J Drsata et al.
Die Pharmazie, 54(9), 713-714 (1999-10-16)
D W Konas et al.
The Journal of organic chemistry, 66(26), 8831-8842 (2001-12-26)
Electrophilic fluorination of enantiomerically pure 2-pyrrolidinones (4) derived from (L)-glutamic acid has been investigated as a method for the synthesis of single stereoisomers of 4-fluorinated glutamic acids. Reaction of the lactam enolate derived from 9 with NFSi results in a
J Dubois et al.
The Journal of biological chemistry, 258(13), 7897-7899 (1983-07-10)
Two pentapeptides Phe-Leu-X-Glu-Val where X is either the L-threo-gamma-fluoroglutamic acid or the L-erythro-isomer have been synthesized and tested as substrates in the vitamin K-dependent carboxylation. Both peptides are carboxylated, but the reaction occurs exclusively on the glutamic acid of the
Clár Donnelly et al.
Applied microbiology and biotechnology, 77(3), 699-703 (2007-09-29)
Fluorinated amino acids are used as enzyme inhibitors, mechanistic probes and in the production of pharmacologically active peptides. Because enantiomerically pure 4-fluoroglutamate is difficult to prepare, the selective degradation of the L-isomer is a potentially convenient method of obtaining D-4-fluoroglutamate
Jun Nakamura et al.
Applied and environmental microbiology, 73(14), 4491-4498 (2007-05-22)
Corynebacterium glutamicum is a biotin auxotroph that secretes L-glutamic acid in response to biotin limitation; this process is employed in industrial L-glutamic acid production. Fatty acid ester surfactants and penicillin also induce L-glutamic acid secretion, even in the presence of

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