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质量水平
方案
≥98.5% (sum of enantiomers)
表单
liquid
旋光性
[α]20/D +22±2°, c = 10% in chloroform
折射率
n20/D 1.403
密度
0.921 g/mL at 20 °C (lit.)
官能团
ether
hydroxyl
SMILES字符串
COC[C@H](C)O
InChI
1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3/t4-/m0/s1
InChI key
ARXJGSRGQADJSQ-BYPYZUCNSA-N
应用
(S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:
- (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
- Thiazolopyridine urea derivatives.
- Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.
Discovery of new quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors and their anticancer activities-Part 1
Bioorganic & medicinal chemistry letters, 29(4), 591-596 (2019)
Stereocontrolled C (sp 3)-P bond formation with non-activated alkyl halides and tosylates
Royal Society of Chemistry Advances, 7(40), 24652-24656 (2017)
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA gyrase B
Journal of Medicinal Chemistry, 56(21), 8834-8848 (2013)
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