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Merck
CN

86971

Fmoc-Dab(Boc)-OH

≥97.0% (HPLC)

别名:

Nα-芴甲氧羰基-Nγ-叔丁氧羰基-L-2,4-二氨基丁酸

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关于此项目

经验公式(希尔记法):
C24H28N2O6
化学文摘社编号:
分子量:
440.49
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
6250328
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产品名称

Fmoc-Dab(Boc)-OH, ≥97.0% (HPLC)

InChI

1S/C24H28N2O6/c1-24(2,3)32-22(29)25-13-12-20(21(27)28)26-23(30)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

SMILES string

CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI key

LIWKOFAHRLBNMG-FQEVSTJZSA-N

assay

≥97.0% (HPLC)

form

powder

optical activity

[α]20/546 −14.5±1°, c = 1% in methanol

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Boc
Fmoc

storage temp.

2-8°C

Quality Level

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ronald Domalaon et al.
Amino acids, 46(11), 2517-2530 (2014-07-30)
Taking a minimalistic approach in efforts to lower the cost for the development of new synthetic antimicrobial peptides, ultrashort cationic lipopeptides were designed to mimic the amphiphilic nature crucial for their activity but with only a very short peptide sequence
Kuo-Yuan Hung et al.
European journal of medicinal chemistry, 136, 154-164 (2017-05-12)
The 20-residue linear peptide A20FMDV2 has been shown to exhibit high selectivity and affinity for the tumour-related αvβ6 integrin and has potential as a vector for therapeutic drugs. However, it exhibits poor half-life in plasma in part due to its
Tony Velkov et al.
Cell chemical biology, 25(4), 380-391 (2018-02-06)
Resistance to the last-resort antibiotic colistin is now widespread and new therapeutics are urgently required. We report the first in toto chemical synthesis and pre-clinical evaluation of octapeptins, a class of lipopeptides structurally related to colistin. The octapeptin biosynthetic cluster consisted

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