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质量水平
方案
98%
表单
powder
mp
186-188 °C (lit.)
官能团
carboxylic acid
hydroxyl
ketone
储存温度
2-8°C
SMILES字符串
CC(\C=C\C1(O)C(C)=CC(=O)CC1(C)C)=C\C(O)=O
InChI
1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-
InChI key
JLIDBLDQVAYHNE-LXGGSRJLSA-N
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一般描述
2-cis,4-trans-脱落酸(ABA)是一种有机物，用作有机合成的起始原料。也用作不对称合成中的手性助剂。ABA衍生物可作为手性模板诱导特定产物的生成，用于控制反应的立体化学性质。
应用
- 脱落酸的手性分离：研究展示了使用苯基柱和γ-环糊精流动相的高效液相色谱法进行的脱落酸的直接手性分离，推动了植物应激激素研究所必需的分析方法的进步（Terashima et al., 2023）。
- 黄嘌呤氧化酶抑制活性：一项涉及脱落酸衍生物的研究表明，黄嘌呤氧化酶具有显著的抑制活性，具有潜在的健康益处和治疗应用（Miyata et al., 2019）。
- 抗癌潜力：来自红树林内生真菌的含脱落酸提取物具有细胞毒性特性，并诱导人癌症细胞的G（0）/G（1）细胞周期停滞和凋亡，研究突出了其在癌症治疗策略中的潜力（Zhou et al., 2018）。
- 抗糖尿病活性：来自内生真菌的含脱落酸提取物显示出抗糖尿病活性前景，通过天然产物研究可能增加糖尿病的治疗选择（Uzor et al., 2017）。
- 葡萄糖耐受性和胰岛素血症的下降：一项突破性的研究发现，水果提取物中微克量的脱落酸显著提高了大鼠和人类的葡萄糖耐受性，降低了胰岛素水平，这表明它可以作为治疗糖尿病的膳食补充剂（Magnone et al., 2015）。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Scott Hayes et al.
Current biology : CB, 29(10), 1669-1676 (2019-05-06)
Global food production is set to keep increasing despite a predicted decrease in total arable land [1]. To achieve higher production, denser planting will be required on increasingly degraded soils. When grown in dense stands, crops elongate and raise their
Scott A M McAdam et al.
The New phytologist, 198(2), 429-441 (2013-02-21)
Little is known about how a predominantly passive hydraulic stomatal control in ferns and lycophytes might impact water use under stress. Ferns and lycophytes occupy a diverse array of habitats, from deserts to rainforest canopies, raising the question of whether
Haifeng Jia et al.
The New phytologist, 198(2), 453-465 (2013-02-22)
Fleshy fruits are classically divided into climacteric and nonclimacteric types. It has long been thought that the ripening of climacteric and nonclimacteric fruits is regulated by ethylene and abscisic acid (ABA), respectively. Here, we report that sucrose functions as a
Mirko Magnone et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(12), 4783-4793 (2015-08-06)
2-Cis,4-trans-abscisic acid (ABA) is a plant hormone that is present also in animals. Several lines of evidence suggest that ABA contributes to the regulation of glycemia in mammals: nanomolar ABA stimulates insulin release from β-pancreatic cells and glucose transporter-4-mediated glucose
Mei Hua Cui et al.
FEBS letters, 587(12), 1773-1778 (2013-05-11)
We have characterized the function of a plant R2R3-MYB transcription factor, Arabidopsis thaliana MYB20 (AtMYB20). Transgenic plants overexpressing AtMYB20 (AtMYB20-OX) enhanced salt stress tolerance while repression lines (AtMYB20-SRDX) were more vulnerable to NaCl than wild-type plants. Following NaCl treatment, the
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