所有图片(1)
About This Item
经验公式（希尔记法）:
C16H19N3O5S
CAS号:
分子量:
365.40
Beilstein:
5795805
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
98%
表单
powder
旋光性
[α]25/D +51°, c = 2 in DMF: AcOH (99:1)
mp
163-165 °C (lit.)
溶解性
methanol: 25 mg/mL, clear, colorless to greenish-yellow
官能团
ester
nitro
thioether
SMILES字符串
[O-][N+](=O)c1ccc(OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)cc1
InChI
1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
InChI key
YUDNXDTXQPYKCA-YDHLFZDLSA-N
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应用
(+)-生物素-4-硝基苯酯可用于在细胞蛋白摄取研究中制备生物素标记ARC（腺苷-寡聚精氨酸偶联物）衍生物。也可用于制备生物素化喹唑啉衍生物抑制VEGFR-2酪氨酸（血管内皮生长因子受体-2）激酶活性。(+)-生物素-4-硝基苯酯在Na[17O]H存在下，水解形成[17O2]生物素用于17O核磁共振波谱法分析蛋白-配体大复合物。
使用Synple自动合成平台(SYNPLE-SC002)实现自动化生物素标记
使用Synple自动合成平台(SYNPLE-SC002)实现自动化生物素标记
包装
无底玻璃瓶。内含物装在插入的融合锥内。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Solid-State 17O NMR Spectroscopy of Large Protein-Ligand Complexes.
Zhu J, et al.
Angewandte Chemie (International Edition in English), 49(45), 8399-8402 (2010)
Isabel Amador-Martínez et al.
American journal of physiology. Renal physiology, 317(2), F275-F285 (2019-05-23)
Major cardiovascular events are a common complication in patients with chronic kidney disease (CKD). Endothelial dysfunction can contribute to the cardiovascular injury observed in CKD. Here, we used a rat model of acute kidney injury to CKD transition to investigate
Jingui Xue et al.
Journal of alternative and complementary medicine (New York, N.Y.), 25(8), 856-860 (2019-07-12)
Objectives: Chronic heart failure (CHF) is a chronic and progressive disease with high incidence. The aim of this study
Identification of the ability of highly charged nanomolar inhibitors of protein kinases to cross plasma membranes and carry a protein into cells.
Uri A, et al.
Bioorganic & Medicinal Chemistry Letters, 12(16), 2117-2120 (2002)
Eiichi Akiyama et al.
ESC heart failure, 7(3), 996-1006 (2020-04-12)
Changes in echocardiographic parameters and biomarkers of cardiac and venous pressures or estimated plasma volume during hospitalization associated with decongestive treatments in acute heart failure (AHF) patients with either preserved left ventricular ejection fraction (LVEF) (HFPEF) or reduced LVEF (HFREF)
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