861650
(+)-生物素 4-硝基苯酯
98%
别名:
4-硝基苯基 (+)-生物素酯, d-生物素对硝基苯酯, BNP
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关于此项目
经验公式（希尔记法）:
C16H19N3O5S
化学文摘社编号:
分子量:
365.40
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5795805
Assay:
98%
Form:
powder
InChI key
YUDNXDTXQPYKCA-YDHLFZDLSA-N
SMILES string
[O-][N+](=O)c1ccc(OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)cc1
InChI
1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
assay
98%
form
powder
optical activity
[α]25/D +51°, c = 2 in DMF: AcOH (99:1)
Quality Level
mp
163-165 °C (lit.)
solubility
methanol: 25 mg/mL, clear, colorless to greenish-yellow
functional group
ester, nitro, thioether
Application
(+)-生物素-4-硝基苯酯可用于在细胞蛋白摄取研究中制备生物素标记ARC（腺苷-寡聚精氨酸偶联物）衍生物。也可用于制备生物素化喹唑啉衍生物抑制VEGFR-2酪氨酸（血管内皮生长因子受体-2）激酶活性。(+)-生物素-4-硝基苯酯在Na[17O]H存在下，水解形成[17O2]生物素用于17O核磁共振波谱法分析蛋白-配体大复合物。
使用Synple自动合成平台(SYNPLE-SC002)实现自动化生物素标记
使用Synple自动合成平台(SYNPLE-SC002)实现自动化生物素标记
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Solid-State 17O NMR Spectroscopy of Large Protein-Ligand Complexes.
Zhu J, et al.
Angewandte Chemie (International Edition in English), 49(45), 8399-8402 (2010)
Björn Redfors et al.
Circulation (2018-04-19)
Background -Elevated B-type natriuretic peptide (BNP) is reflective of impaired cardiac function and is associated with worse prognosis among
Isabel Amador-Martínez et al.
American journal of physiology. Renal physiology, 317(2), F275-F285 (2019-05-23)
Major cardiovascular events are a common complication in patients with chronic kidney disease (CKD). Endothelial dysfunction can contribute to the cardiovascular injury observed in CKD. Here, we used a rat model of acute kidney injury to CKD transition to investigate
Jingui Xue et al.
Journal of alternative and complementary medicine (New York, N.Y.), 25(8), 856-860 (2019-07-12)
Objectives: Chronic heart failure (CHF) is a chronic and progressive disease with high incidence. The aim of this study
Clemens M Ortner et al.
Anesthesia and analgesia, 128(6), 1208-1216 (2019-05-17)
Pilot studies applying point-of-care ultrasound (POCUS) in preeclampsia indicate the presence of pulmonary interstitial edema, cerebral edema, and cardiac dysfunction. Laboratory markers of oncotic pressure (albumin) and cardiac dysfunction (brain natriuretic peptide [BNP]) may be abnormal, but the clinical application
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