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Merck
CN

861065

天青 II

powder

别名:

3-氯-6-羟基-2-吡啶羧酸, 天青II

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关于此项目

线性分子式:
C16H18N3S · C15H16N3S ·2 Cl
化学文摘社编号:
分子量:
625.68
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
Colour Index Number:
52010/52015
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产品名称

天青 II, powder

SMILES string

[Cl-].[Cl-].CNc1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](\C)C.CN(C)c4ccc5N=C6C=C\C(C=C6Sc5c4)=[N+](\C)C

InChI

1S/C16H18N3S.C15H15N3S.2ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;1-16-10-4-6-12-14(8-10)19-15-9-11(18(2)3)5-7-13(15)17-12;;/h5-10H,1-4H3;4-9H,1-3H3;2*1H/q+1;;;/p-1

InChI key

YOWZJZJLXUQHGF-UHFFFAOYSA-M

description

mixture of Azure B and Methylene Blue in equal amounts.

form

powder

solubility

water: soluble

λmax

657 nm

ε (extinction coefficient)

≥1500 at 652-658 nm in water at 0.003 g/L
≥400 at 243-249 nm in water at 0.003 g/L
≥800 at 288-294 nm in water at 0.003 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Azure II 已用于溶酶体糖原染色 Richardson 储备液。在过碘酸雪夫染色过程中也用于糖原、细胞核和细胞质的染色。

Biochem/physiol Actions

Azure II 复合物用于细胞核、杯状细胞、横纹肌、内皮细胞、平滑肌、细胞质、脂滴、红细胞、糖原、胶原、软骨、粘液颗粒、弹性蛋白和白细胞的染色。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Haley R Noonan et al.
Disease models & mechanisms, 9(8), 873-884 (2016-08-05)
Patients with von Hippel-Lindau (VHL) disease harbor a germline mutation in the VHL gene leading to the development of several tumor types including clear cell renal cell carcinoma (ccRCC). In addition, the VHL gene is inactivated in over 90% of
Nelson S Yee et al.
Disease models & mechanisms, 4(2), 240-254 (2010-12-25)
Genetic analysis of pancreatic development has provided new insights into the mechanisms underlying the formation of exocrine pancreatic neoplasia. Zebrafish sweetbread (swd) mutants develop hypoplastic acini and dysmorphic ducts in the exocrine pancreas, with impeded progression of cell division cycle

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