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Merck
CN

860417

水杨酰胺

99%

别名:

2-羟基苯甲酰胺

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关于此项目

线性分子式:
2-(HO)C6H4CONH2
化学文摘社编号:
分子量:
137.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-609-3
Beilstein/REAXYS Number:
742439
MDL number:
Assay:
99%
Form:
solid
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InChI

1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)

InChI key

SKZKKFZAGNVIMN-UHFFFAOYSA-N

SMILES string

NC(=O)c1ccccc1O

assay

99%

form

solid

mp

140-144 °C (lit.)

Quality Level

Gene Information

human ... AR(367)

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General description

水杨酰胺可用作酰化反应合成取代水杨酰胺的起始原料。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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分析证书(COA)

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Acylation of salicylamide to 5-acetylsalicylamide using ionic liquids as dual catalyst and solvent
Chen, W et al.
Journal of Industrial and Engineering Chemistry, 16(5), 800-804 (2010)
Patricia D Sauzem et al.
European journal of medicinal chemistry, 43(6), 1237-1247 (2007-09-25)
In this work, we reported the synthesis and evaluation of the analgesic and anti-inflammatory properties of novel 3- or 4-substituted 5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-1-carboxyamidepyrazoles (where 3-/4-substituent=H/H, Me/H, Et/H, Pr/H, i-Pr/H, Bu/H, t-Bu/H, Ph/H, 4-Br-Ph/H and H/Me) designed in the exploration of the bioisosteric
J A Murillo Pulgarín et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 909-914 (2011-05-13)
A new methodology for the simultaneous determination of salicylic acid and salicylamide in biological fluids is proposed. The strong overlapping of the fluorescence spectra of both analytes makes impossible the conventional fluorimetric determination. For that reason, the use of fluorescence
R Dolezal et al.
European journal of medicinal chemistry, 44(2), 869-876 (2008-06-13)
Quantitative relationships between the molecular structure and the biological activity of 49 isosteric salicylamide derivatives as potential antituberculotics with a new mechanism of action against three Mycobacterial strains were investigated. The molecular structures were represented by quantum chemical B3LYP/6-31G( *)
Xiaoyan Zhou et al.
Dalton transactions (Cambridge, England : 2003), 41(6), 1765-1775 (2011-12-14)
Two new flexible exo-bidentate ligands were designed and synthesized, incorporating different backbone chain lengths bearing two salicylamide arms, namely 2,2'-(2,2'-oxybis(ethane-2,1-diyl)bis(oxy))bis(N-benzylbenzamide) (L(I)) and 2,2'-(2,2'-(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(N-benzylbenzamide) (L(II)). These two structurally related ligands are used as building blocks for constructing diverse lanthanide polymers with

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