生物来源
synthetic
检测方案
99%
形式
powder
mp
226-228 °C (lit.)
SMILES字符串
OC(=O)\C=C\c1c[nH]cn1
InChI
1S/C6H6N2O2/c9-6(10)2-1-5-3-7-4-8-5/h1-4H,(H,7,8)(H,9,10)/b2-1+
InChI key
LOIYMIARKYCTBW-OWOJBTEDSA-N
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一般描述
4-咪唑丙烯酸也被称为尿烷酸，是衍生自组氨酸的一种天然代谢产物。它在300-280 nm范围内的UV-B区域具有强吸收光谱，因此可用过UV发色团。
应用
4-咪唑丙烯酸可作为前体，用于合成（±）-高组氨酸、尿酸修饰的壳聚糖、以及 N1-芳基（杂芳基）烷基-N2-[3-（1H-咪唑-4-（基）丙基]胍。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Harm C Arentsen et al.
The Journal of urology, 187(4), 1445-1449 (2012-02-22)
We determined the effect of protodynamic therapy against bladder cancer cells in vitro and in vivo. We investigated cis-urocanic acid in rat bladder cancer cell cultures and in an orthotopic rat urothelial carcinoma model to assess its safety and antiproliferative
Acylguanidines as bioisosteres of guanidines: N G-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists
Ghorai P, et al.
Journal of Medicinal Chemistry, 51(22), 7193-7204 (2008)
Efficient gene delivery by urocanic acid-modified chitosan
Kim TH, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 93(3), 389-402 (2003)
Claudia L Kleinman et al.
Nucleic acids research, 45(10), 5757-5769 (2017-03-24)
LuxR-type transcription factors control diverse physiological functions necessary for bacterial adaptation to environmental changes. In the intracellular pathogen Brucella, the LuxR homolog VjbR has been shown to regulate the expression of virulence factors acting at early stages of the intracellular
A theoretical study of the low-lying excited states of trans-and cis-urocanic acid
Page CS, et al.
The Journal of Physical Chemistry A, 103(48), 9864-9871 (1999)
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