推荐产品
质量水平
检测方案
98%
形式
crystals
mp
>300 °C (lit.)
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].NC(=N)c1ccc(N)cc1
InChI
1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10;;/h1-4H,8H2,(H3,9,10);2*1H
InChI key
GHEHNICLPWTXJC-UHFFFAOYSA-N
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应用
4-二盐酸氨基苯甲脒可用于合成：
- 基于苯甲脒的口服活性纤维蛋白原受体拮抗剂。
- 苯甲脒衍生物，其是选择性和有效的丝氨酸蛋白酶抑制剂。
- 新型吡咯并[3,2-c]喹啉，其是拓扑异构酶抑制剂（例如甲氧檗因和法格罗宁）的结构类似物。
4-二盐酸氨基苯甲脒在亲和层析中可用作配体，用于酶的纯化和固定。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Design of orally active, non-peptide fibrinogen receptor antagonists. An evolutionary process from the RGD sequence to novel anti-platelet aggregation agents.
Bovy P R, et al.
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Biochemical and molecular modeling analysis of the ability of two p-aminobenzamidine-based sorbents to selectively purify serine proteases (fibrinogenases) from snake venoms.
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Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 822(1-2), 1-9 (2005)
Specific adsorption of serine proteases on coated silica beads substituted with amidine derivatives.
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Journal of chromatography, 510, 123-132 (1990-06-27)
Amidine derivatives interact with serine proteases, the inhibition being due to interactions between amidine functions and the active sites of the enzymes. Five different types of amidine (substituted or unsubstituted) were coupled to coated silica beads, which had previously been
A L Nguyen et al.
Enzyme and microbial technology, 12(9), 663-668 (1990-09-01)
A reactive water-soluble polymer was synthesized by copolymerizing N-isopropylacrylamide and glycidyl acrylate. The reactive polymer could react with the amino groups of enzymes/proteins or other ligands to form an affinity polymer. As a model, the reactive polymer was allowed to
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