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质量水平
方案
96%
表单
powder
mp
52-55 °C (lit.)
官能团
ketone
SMILES字符串
CC(C)(c1cccnc1)C(=O)c2cccnc2
InChI
1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
InChI key
FJLBFSROUSIWMA-UHFFFAOYSA-N
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应用
2-甲基-1,2-二-3-吡啶基-1-丙酮通过阻断脱氧皮质酮向皮质酮的转化而抑制皮质酮的生物合成。 它广泛用于肾上腺皮质相关的临床研究。
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
The relationship between adrenocortical function and Hsp70 expression in socially isolated Japanese quail.
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology, 161(2), 140-144 (2012)
Secretion of cortisol and aldosterone as a vulnerable target for adrenal endocrine disruption?screening of 30 selected chemicals in the human H295R cell model.
Journal of Applied Toxicology, 28(8), 1045-1053 (2008)
Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: a metabolomics approach.
Chemical Research in Toxicology, 25(8), 1720-1731 (2012)
The Journal of experimental biology, 220(Pt 6), 1056-1064 (2017-01-14)
The zebrafish (Danio rerio) has become a well-established experimental model in many research fields but the loss of the primary sex-determining region during the process of domestication renders laboratory strains of zebrafish susceptible to the effects of environmental factors on
The Journal of steroid biochemistry and molecular biology, 129(3-5), 129-138 (2012-01-03)
In order to overcome many limitations of immunoassays, high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) has the potential to find its place in the clinical laboratory medicine for quantification of steroid hormones. A prerequisite for the application of a new
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