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质量水平
检测方案
98%
形式
solid
反应适用性
reaction type: solution phase peptide synthesis
mp
≥300 °C
应用
peptide synthesis
SMILES字符串
CC(C)(N)C(O)=O
InChI
1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
InChI key
FUOOLUPWFVMBKG-UHFFFAOYSA-N
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相关类别
一般描述
2-氨基异丁酸又名α-氨基丁酸，是一种氨基酸，用于液相多肽合成法。强烈促进肽形成螺旋，适合作为肽合成构件。
应用
2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代，对C−H提取呈惰性，因而在肽链中掺入这种化合物可避免发生不需要的反应。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Photochemical methods for peptide macrocyclisation
Chemistry?A European Journal , 27, 69-88 (2021)
Amphiphilic polypeptides with prolonged enzymatic stability for the preparation of self-assembled nanobiomaterials
Royal Society of Chemistry Advances, 8, 34603-34613 (2018)
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
Evgeniy Salnikov et al.
Journal of biomolecular NMR, 45(4), 373-387 (2009-10-14)
In protein NMR spectroscopy the chemical shift provides important information for the assignment of residues and a first structural evaluation of dihedral angles. Furthermore, angular restraints are obtained from oriented samples by solution and solid-state NMR spectroscopic approaches. Whereas the
Marta De Zotti et al.
Amino acids, 43(4), 1761-1777 (2012-04-10)
The lipopeptaibol trichogin GA IV is a natural, non-ribosomally synthesized, antimicrobial peptide remarkably resistant to the action of hydrolytic enzymes. This feature may be connected to the multiple presence in its sequence of the non-coded residue α-aminoisobutyric acid (Aib), which
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