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Merck
CN

850993

Sigma-Aldrich

2-氨基异丁酸

98%, for peptide synthesis

别名:

α-氨基异丁酸, 2-甲基丙氨酸, Aib

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About This Item

线性分子式:
(CH3)2C(NH2)COOH
CAS号:
分子量:
103.12
Beilstein:
506496
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22

产品名称

2-氨基异丁酸, 98%

质量水平

方案

98%

表单

solid

反应适用性

reaction type: solution phase peptide synthesis

mp

≥300 °C

应用

peptide synthesis

SMILES字符串

CC(C)(N)C(O)=O

InChI

1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)

InChI key

FUOOLUPWFVMBKG-UHFFFAOYSA-N

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一般描述

2-氨基异丁酸又名α-氨基丁酸,是一种氨基酸,用于液相多肽合成法。强烈促进肽形成螺旋,适合作为肽合成构件。

应用

2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代,对C−H提取呈惰性,因而在肽链中掺入这种化合物可避免发生不需要的反应。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Photochemical methods for peptide macrocyclisation
Chemistry?A European Journal , 27, 69-88 (2021)
C Lucarelli et al.
Journal of chromatography, 541(1-2), 285-296 (1991-03-22)
A procedure is described for the determination of alpha-methyldopa (MD) [L-3-(3,4-dihydroxyphenyl)-2-methylalanine], its metabolite and catecholamines in the urine and plasma of patients undergoing MD therapy, by high-performance liquid chromatography with dual working electrode coulometric detection. An efficient sample preparation procedure
Amphiphilic polypeptides with prolonged enzymatic stability for the preparation of self-assembled nanobiomaterials
Royal Society of Chemistry Advances, 8, 34603-34613 (2018)
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
Jamie E Elsila et al.
Astrobiology, 11(2), 123-133 (2011-03-23)
The presence of nonprotein α-dialkyl-amino acids such as α-aminoisobutyric acid (α-AIB) and isovaline (Iva), which are considered to be relatively rare in the terrestrial biosphere, has long been used as an indication of the indigeneity of meteoritic amino acids. However

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