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产品名称
2-氨基异丁酸, 98%
质量水平
方案
98%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
mp
≥300 °C
应用
peptide synthesis
SMILES字符串
CC(C)(N)C(O)=O
InChI
1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
InChI key
FUOOLUPWFVMBKG-UHFFFAOYSA-N
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一般描述
2-氨基异丁酸又名α-氨基丁酸，是一种氨基酸，用于液相多肽合成法。强烈促进肽形成螺旋，适合作为肽合成构件。
应用
2-氨基异丁酸可用于合成自组装多肽纳米颗粒。 结构上二-α-取代，对C−H提取呈惰性，因而在肽链中掺入这种化合物可避免发生不需要的反应。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Photochemical methods for peptide macrocyclisation
Chemistry?A European Journal , 27, 69-88 (2021)
Amphiphilic polypeptides with prolonged enzymatic stability for the preparation of self-assembled nanobiomaterials
Royal Society of Chemistry Advances, 8, 34603-34613 (2018)
Yutong Yang et al.
Membranes, 10(11) (2020-11-14)
Amine-containing mixed-matrix membranes incorporated with amino-functionalized multi-walled carbon nanotubes (AF-MWNTs) were synthesized for CO2/H2 separation based on the facilitated transport mechanism. AF-MWNTs were chosen primarily as the mechanical reinforcing filler to enhance the membrane stability. At 107 °C and 0.2-MPa
C Lucarelli et al.
Journal of chromatography, 541(1-2), 285-296 (1991-03-22)
A procedure is described for the determination of alpha-methyldopa (MD) [L-3-(3,4-dihydroxyphenyl)-2-methylalanine], its metabolite and catecholamines in the urine and plasma of patients undergoing MD therapy, by high-performance liquid chromatography with dual working electrode coulometric detection. An efficient sample preparation procedure
Alessandro Donoli et al.
Organic letters, 13(6), 1282-1285 (2011-02-24)
Two series of 3(10)-helical peptides of different lengths and rigidity, based on the strongly foldameric α-aminoisobutyric acid and containing a terminal ferrocenyl unit, have been synthesized. Oxidation-state sensitive spectroscopic tags of helical peptides, the N-H groups, allowed mapping of the
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