等级
technical
质量水平
形式
solution
浓度
~50% in DMF
SMILES字符串
CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1
InChI
1S/C9H21O6P3/c1-4-7-16(10)13-17(11,8-5-2)15-18(12,14-16)9-6-3/h4-9H2,1-3H3
InChI key
PAQZWJGSJMLPMG-UHFFFAOYSA-N
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一般描述
Propylphosphonic anhydride is a highly reactive cyclic anhydride that is commonly used as a coupling agent and water scavenger.
应用
Coupling reagent for peptide synthesis; Preparation of other amides; Synthesis of esters (depsipeptides)
特点和优势
Some of its unique features include:
- Broad functional group tolerance
- Low epimerization tendency
- By-products are water-soluble
- High yield and purity
法律信息
T3P is a registered trademark of Archimica GmbH
警示用语:
Danger
危险分类
Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
WGK
WGK 2
闪点(°F)
143.6 °F
闪点(°C)
62 °C
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
Phosph. Sulfur Relat. Elem., 30, 645-645 (1986)
Liebigs Ann. Chem., 1-1 (1986)
Angewandte Chemie (International Edition in English), 92, 129-129 (1980)
Journal of the American Chemical Society, 108, 181-181 (1986)
Propylphosphonic anhydride (T3P?): an efficient reagent for the one-pot synthesis of 1, 2, 4-oxadiazoles, 1, 3, 4-oxadiazoles, and 1, 3, 4-thiadiazoles.
Tetrahedron, 65(48), 9989-9996 (2009)
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