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Merck
CN

808482

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide 50:50, acid and hydroxy terminated, Mn 25000

别名:

HO-PLGA-COOH, PLGA, 异双功能 PLGA

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线性分子式:
HO(C3H4O2)x(C2H2O2)yH
UNSPSC Code:
12162002
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form

crystals

mol wt

Mn 25000

storage temp.

2-8°C

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Application

用于药物输送应用的偶联、移植和功能化的异双功能可降解 PLGA。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Saurabh Srivastava et al.
Journal of cancer research and therapeutics, 15(3), 480-490 (2019-06-07)
The aim of the study to develop surface modified targeted moiety α-tocopherol (α-t) encapsulated with 5-fluorouracil (5-FU)-poly-D, L-lactic-co-glycolic acid nanoparticles (PLGA NPs) toward the anticancer activity against oral squamous cell carcinoma (OSCC). 5-FU was conjugated with the polymer, PLGA by
Grafting of telechelic poly(lactic-co-glycolic acid) onto O2 plasma-treated polypropylene flakes.
Ren J, et al.
Journal of Applied Polymer Science, 121, 210-216 (2011)
Kun Wei et al.
International journal of pharmaceutics, 464(1-2), 225-233 (2014-01-28)
Di-block polymer of poly (lactic-co-glycolic acid)-poly (ethylene glycol) (PLGA-PEG) end-capped with capecitabine (CAP) at the hydrophobic domain and folate (FA) at hydrophilic domain were synthesized respectively. The products were extensively studied by nuclear magnetic resonance ((1)H NMR) and gel permeation

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