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Merck
CN

808482

Sigma-Aldrich

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide 50:50, acid and hydroxy terminated, Mn 25000

别名:

HO-PLGA-COOH, PLGA, 异双功能 PLGA

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About This Item

线性分子式:
HO(C3H4O2)x(C2H2O2)yH
UNSPSC代码:
12162002

表单

crystals

分子量

Mn 25000

储存温度

2-8°C

应用

用于药物输送应用的偶联、移植和功能化的异双功能可降解 PLGA。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Saurabh Srivastava et al.
Journal of cancer research and therapeutics, 15(3), 480-490 (2019-06-07)
The aim of the study to develop surface modified targeted moiety α-tocopherol (α-t) encapsulated with 5-fluorouracil (5-FU)-poly-D, L-lactic-co-glycolic acid nanoparticles (PLGA NPs) toward the anticancer activity against oral squamous cell carcinoma (OSCC). 5-FU was conjugated with the polymer, PLGA by
Kun Wei et al.
International journal of pharmaceutics, 464(1-2), 225-233 (2014-01-28)
Di-block polymer of poly (lactic-co-glycolic acid)-poly (ethylene glycol) (PLGA-PEG) end-capped with capecitabine (CAP) at the hydrophobic domain and folate (FA) at hydrophilic domain were synthesized respectively. The products were extensively studied by nuclear magnetic resonance ((1)H NMR) and gel permeation
Grafting of telechelic poly(lactic-co-glycolic acid) onto O2 plasma-treated polypropylene flakes.
Ren J, et al.
Journal of Applied Polymer Science, 121, 210-216 (2011)

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