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Merck
CN

802360

Olefin Metathesis in a Box

greener alternative
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UNSPSC Code:
12352300
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greener alternative product characteristics

Waste Prevention
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

storage temp.

2-8°C

Application

This second-generation kit contains the reagents, catalyst, and solvent required to perform olefin methathesis in TPGS-750-M, a surfactant developed by the Lipshutz group as a greener alternative to organic solvents. This technology allows common metal-catalyzed reactions to be run under aqueous conditions, considerably reducing solvent waste. The components are pre-weighed in the appropriate amounts for a 0.5mmol scale reaction.

Please refer to the attached Protocol for details.

wgk

WGK 3

存储类别

10 - Combustible liquids

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Sol. 2

法规信息

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Bruce H Lipshutz et al.
The Journal of organic chemistry, 76(11), 4379-4391 (2011-05-10)
An environmentally benign surfactant (TPGS-750-M), a diester composed of racemic α-tocopherol, MPEG-750, and succinic acid, has been designed and readily prepared as an effective nanomicelle-forming species for general use in metal-catalyzed cross-coupling reactions in water. Several "name" reactions, including Heck
Bruce H Lipshutz et al.
Angewandte Chemie (International ed. in English), 52(42), 10952-10958 (2013-09-14)
Transition-metal-catalyzed carbon-carbon and carbon-heteroatom bond formations are among the most heavily used types of reactions in both academic and industrial settings. As important as these are to the synthetic community, such cross-couplings come with a heavy price to our environment

相关内容

Designer surfactants enable diverse transformations like Suzuki-Miyaura, Olefin Metathesis, and 1,4-Addition to Enones in water by Prof. Bruce Lipshutz.

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