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一般描述
Fluorescent nanodiamonds (FNDs) can be prepared by subjecting synthetic diamond nanocrystallites to helium ions. FND is biocompatible and its surface can be easily functionalized. It is a very useful tool in bioimaging mainly because the photons emitted from the defect centers of FND upon laser excitation can easily penetrate the tissue. The emission from FNDs is extremely stable. The average size of the FNDs is 100 nm.
In fluorescent nanodiamonds, the nitrogen vacancy centers in the diamond lattice provide the fluorescence; unlike the quantum dots or organic dyes, the color centers in these don′t photobleach or photoblink. These outstanding properties of fluorescent nanodiamonds along with their biocompatibility, large surface area etc. make them promising bioimaging probes.
产品可使用羧酸、羟基、酮、醚和/或氢进行功能化。
应用
Potential uses of FNDs are as in vivo nanoprobe for bioimaging, cell labelling and cell tracking.
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Nanodiamonds for optical bioimaging
Y. Y. Hui, C-L Cheng, and H-C Chang
Journal of Physics D: Applied Physics, 43(37), 374021-374021 (2010)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting
B-M Chang, H-S Lin, L-J Su, et al.
Advances in Functional Materials, 23(46), 5737-5745 (2013)
The Exocytosis of Fluorescent Nanodiamond and Its Use as a Long-Term Cell Tracker
Fang CY, et al.
Small, 7(23), 3363-3370 (2011)
Mass production and dynamic imaging of fluorescent nanodiamonds
Chang YR, et al.
Nature Nanotechnology, 3(5), 284-288 (2008)
商品
Fluorescent Nanodiamonds and biofunctionalization strategies are detailed for imaging and bioconjugation applications.
Fluorescent Nanodiamond Particles (FNDs)- Find properties and applications of nanodiamond particles.
荧光纳米金刚石颗粒（FND）- 发现纳米金刚石颗粒的属性和应用。
Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.
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