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Merck
CN

78110

Sigma-Aldrich

Phe-Gly 水合物

≥98.0% (dried material)

别名:

L-苯丙氨酰-甘氨酸 水合物

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About This Item

线性分子式:
C6H5CH2CH(NH2)CONHCH2COOH · aq
CAS号:
分子量:
222.24 (anhydrous basis)
Beilstein:
2218143
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

质量水平

方案

≥98.0% (dried material)

表单

crystals

旋光性

[α]20/D +103±3°, c = 1% in H2O

杂质

≤5% ethanol
≤5% water

mp

~260 °C (dec.)

应用

peptide synthesis

SMILES字符串

O.N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O

InChI

1S/C11H14N2O3.H2O/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8;/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15);1H2/t9-;/m0./s1

InChI key

QNLAQUFDXQTNOW-FVGYRXGTSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Akira Yamamoto et al.
International journal of pharmaceutics, 250(1), 119-128 (2002-12-14)
We synthesized three novel lipophilic derivatives of phenylalanyl-glycine (Phe-Gly), C4-Phe-Gly, C6-Phe-Gly and C8-Phe-Gly by chemical modification with butyric acid (C4), caproic acid (C6) and octanoic acid (C8). The effect of the acylation on the stability, permeability and accumulation of Phe-Gly
S Chakrabarti et al.
Toxicology, 67(1), 15-27 (1991-03-25)
An isomeric mixture of S-[(1 and 2)-phenyl-2-hydroxyethyl]glutathione (PHEG), a glutathione conjugate of styrene, is moderately nephrotoxic. Its in vivo nephrotoxicity was characterized by significant elevations in the urinary excretion of glucose, gamma-glutamyl transpeptidase, glutamate dehydrogenase, N-acetyl-beta-D-glucosaminidase and lactic dehydrogenase 24
Claire E Atkinson et al.
Biophysical journal, 104(1), 37-50 (2013-01-22)
Selective transport through the nuclear pore complex (NPC) requires nucleoporins containing natively unfolded phenylalanine-glycine (FG) domains. Several differing models for their dynamics within the pore have been proposed. We characterize the behavior of the FG nucleoporins in vivo using polarized fluorescence
Peptide ordering within nuclear pores in living cells.
Ronald W Holz
Biophysical journal, 104(1), 6-7 (2013-01-22)
Eun-Kyung Suh et al.
Experimental cell research, 290(2), 447-456 (2003-10-22)
beta-Catenin nuclear import has been found to be independent of classical nuclear localization signal (NLS) nuclear import factors. Here, we test the hypothesis that beta-catenin interacts directly with nuclear pore proteins to mediate its own transport. We show that beta-catenin

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