78110
Phe-Gly 水合物
≥98.0% (dried material)
别名:
L-苯丙氨酰-甘氨酸 水合物
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关于此项目
线性分子式:
C6H5CH2CH(NH2)CONHCH2COOH · aq
化学文摘社编号:
分子量:
222.24 (anhydrous basis)
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
2218143
MDL number:
SMILES string
O.N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O
InChI
1S/C11H14N2O3.H2O/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8;/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15);1H2/t9-;/m0./s1
InChI key
QNLAQUFDXQTNOW-FVGYRXGTSA-N
assay
≥98.0% (dried material)
form
crystals
optical activity
[α]20/D +103±3°, c = 1% in H2O
impurities
≤5% ethanol, ≤5% water
mp
~260 °C (dec.)
application(s)
peptide synthesis
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
S Chakrabarti et al.
Toxicology, 67(1), 15-27 (1991-03-25)
An isomeric mixture of S-[(1 and 2)-phenyl-2-hydroxyethyl]glutathione (PHEG), a glutathione conjugate of styrene, is moderately nephrotoxic. Its in vivo nephrotoxicity was characterized by significant elevations in the urinary excretion of glucose, gamma-glutamyl transpeptidase, glutamate dehydrogenase, N-acetyl-beta-D-glucosaminidase and lactic dehydrogenase 24
Eun-Kyung Suh et al.
Experimental cell research, 290(2), 447-456 (2003-10-22)
beta-Catenin nuclear import has been found to be independent of classical nuclear localization signal (NLS) nuclear import factors. Here, we test the hypothesis that beta-catenin interacts directly with nuclear pore proteins to mediate its own transport. We show that beta-catenin
Akira Yamamoto et al.
International journal of pharmaceutics, 250(1), 119-128 (2002-12-14)
We synthesized three novel lipophilic derivatives of phenylalanyl-glycine (Phe-Gly), C4-Phe-Gly, C6-Phe-Gly and C8-Phe-Gly by chemical modification with butyric acid (C4), caproic acid (C6) and octanoic acid (C8). The effect of the acylation on the stability, permeability and accumulation of Phe-Gly
Peptide ordering within nuclear pores in living cells.
Ronald W Holz
Biophysical journal, 104(1), 6-7 (2013-01-22)
Claire E Atkinson et al.
Biophysical journal, 104(1), 37-50 (2013-01-22)
Selective transport through the nuclear pore complex (NPC) requires nucleoporins containing natively unfolded phenylalanine-glycine (FG) domains. Several differing models for their dynamics within the pore have been proposed. We characterize the behavior of the FG nucleoporins in vivo using polarized fluorescence
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