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Merck
CN

78110

Sigma-Aldrich

Phe-Gly 水合物

≥98.0% (dried material)

别名:

L-苯丙氨酰-甘氨酸 水合物

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About This Item

线性分子式:
C6H5CH2CH(NH2)CONHCH2COOH · aq
CAS号:
分子量:
222.24 (anhydrous basis)
Beilstein:
2218143
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

质量水平

方案

≥98.0% (dried material)

表单

crystals

旋光性

[α]20/D +103±3°, c = 1% in H2O

杂质

≤5% ethanol
≤5% water

mp

~260 °C (dec.)

应用

peptide synthesis

SMILES字符串

O.N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O

InChI

1S/C11H14N2O3.H2O/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8;/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15);1H2/t9-;/m0./s1

InChI key

QNLAQUFDXQTNOW-FVGYRXGTSA-N

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T Fujita et al.
Life sciences, 61(25), 2455-2465 (1997-01-01)
The transport characteristics of chemically modified phenylalanylglycine (Phe-Gly) with butyric acid (C4-Phe-Gly) and caproic acid (C6-Phe-Gly) were examined using rabbit intestinal brush-border membrane vesicles (BBMVs). In the presence of an inwardly H+ gradient (pH 7.5 inside, pH 6.0 outside), the
Jon Våbenø et al.
The Journal of organic chemistry, 67(26), 9186-9191 (2002-12-21)
The readily available N-Boc-protected delta-amino alpha,beta-unsaturated gamma-keto ester 1 was diastereoselectively reduced to the corresponding alcohols 2 and 3, using boron- and aluminum-based reducing reagents. Reduction reactions were successful and resulted in anti/syn ratios of alcohols of >95:5 (80% yield)
A H Dantzig et al.
Biochemical and biophysical research communications, 155(2), 1082-1087 (1988-09-15)
A transport carrier for cephalexin, a cephalosporin antibiotic, was identified in a human intestinal cell line, HT-29. Uptake via the carrier was inhibited by dipeptides, phe-gly, gly-pro, carnosine, and cefaclor, a close drug analog. Uptake was unaffected by the presence
L H Lash et al.
The Journal of biological chemistry, 261(28), 13076-13081 (1986-10-05)
S-(1,2-Dichlorovinyl)glutathione (DCVG) and S-(1,2-dichlorovinyl)-L-cysteine (DCVC) produced time- and concentration-dependent cell death in isolated rat kidney proximal tubular cells. AT-125 blocked and glycylglycine potentiated DCVG toxicity, indicating that metabolism by gamma-glutamyltransferase is required. S-(1,2-Dichlorovinyl)-L-cysteinylglycine, a putative metabolite of DCVG, also produced
S Borg et al.
Journal of medicinal chemistry, 42(21), 4331-4342 (1999-11-02)
Enantiopure heterocyclic Boc-protected Phe-Gly dipeptidomimetics containing 1,3,4-oxadiazole, 1,2,4-oxadiazole, and 1,2,4-triazole ring systems have been synthesized as building blocks in the synthesis of pseudopeptides. Three derivatives (1-3) have the carboxylic acid function directly bound to the heterocyclic ring, and three derivatives

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