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779873

Sigma-Aldrich

甲基-β-环糊精

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% cyclodextrin basis

别名:

Cavasol® W7 M Life Science, MβCD

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About This Item

CAS号:
128446-36-6
UNSPSC代码:
12352201
NACRES:
NA.22

等级

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

质量水平

200

检测方案

≥98.0% cyclodextrin basis

形式

powder

旋光性

[α]/D 154.0 to 156.0°

分子量

Mw 1310 g/mol

标记范围

1.7-1.9 molar substitution

杂质

≤0.10% unsubstituted cyclodextrin
≤0.20% chloride
≤0.50% reducing substances
≤50 ppm volatile organics

灼烧残渣

≤0.50%

缺失

≤5.0% loss on drying

颜色

white to off-white

mp

180-182 °C (lit.)

吸光度

≤0.10 at 350-600 nm in solution at 10%
≤1.00 at 220-350 nm in solution at 10%

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

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相关类别

应用

甲基-β-环糊精是一种大环化合物，可以与许多客体分子形成包合物。与母体β-环糊精相比，它在水溶液中呈现更高的溶解度以及更强的增溶和络合能力。MβCD可用于增强有机溶剂中的酶活性和枯草杆菌蛋白酶的对映选择性。

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。
仅供R&D使用

法律信息

Cavasol is a registered trademark of Wacker Chemie AG

WGK

WGK 3

闪点(°F)

368.6 °F

闪点(°C)

187 °C

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Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.
Ribeiro A
Aaps Pharmscitech, 9(4), 1102-1109 (2008)
Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.
Griebenow K
Journal of the American Chemical Society, 121(36), 8157-8163 (1999)
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Endometrial cancer is the most common gynecologic malignancy diagnosed among women in developed countries. One recent biomarker strongly associated with disease progression and survival is epithelial membrane protein-2 (EMP2), a tetraspan protein known to associate with and modify surface expression
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The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
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