775924
4-Benzoylbenzoic acid N-succinimidyl ester
97%
别名:
4-Benzoylbenzoic acid, succinimidyl ester
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关于此项目
经验公式（希尔记法）:
C18H13NO5
化学文摘社编号:
分子量:
323.30
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
97%
Form:
solid
InChI
1S/C18H13NO5/c20-15-10-11-16(21)19(15)24-18(23)14-8-6-13(7-9-14)17(22)12-4-2-1-3-5-12/h1-9H,10-11H2
SMILES string
O=C1CCC(=O)N1OC(=O)c2ccc(cc2)C(=O)c3ccccc3
InChI key
MVQNJLJLEGZFGP-UHFFFAOYSA-N
assay
97%
form
solid
mol wt
323.3
reaction suitability
reagent type: cross-linking reagent
mp
207-212 °C
storage temp.
−20°C
Application
A benzophenone-based photoreactive reagent shown to be useful for synthesizing photoreactive peptides and oligonucleotides.
Heterobifunctional photoreactive crosslinker. Succinimidyl ester will react with amines and the benzophenone will react non-specifically upon photoirradiation at approximately 360 nm.
Horacio F Olivo et al.
Bioorganic & medicinal chemistry letters, 20(3), 1153-1155 (2009-12-25)
We have synthesized an analog of dehydroepiandrosterone (DHEA, 1) containing both a benzophenone (BP) and a biotin (Bt) group (DHEA-BP-Bt, 8). Compound 8 was prepared by functionalization on C-17 of 1. Biocytin was reacted with 4-benzoylbenzoic acid and the product
Dan Bernardi et al.
Bioorganic & medicinal chemistry letters, 16(6), 1601-1604 (2006-01-03)
The first synthesis of an N-acylated photoactivatable analogue of reduced glutathione is described. N-(4-Benzoylbenzoyl)glutathione (8) was found to be an inhibitor and a photoaffinity probe of purified rat liver glutathione S-transferases.
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