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经验公式(希尔记法):
C12H8N2 · HCl · H2O
化学文摘社编号:
分子量:
234.68
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-325-1
Beilstein/REAXYS Number:
4007967
MDL number:
产品名称
1,10-菲咯啉 盐酸盐 一水合物, ≥99.5% (titration)
form
solid
SMILES string
O.Cl.c1cnc2c(c1)ccc3cccnc23
InChI key
NDLHUHRGAIHALB-UHFFFAOYSA-N
InChI
1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2
assay
≥99.5% (titration)
mp
224-225 °C (lit.)
Quality Level
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Application
1,10-邻菲咯啉盐酸盐单水合物可用作合成以下物质的前体:
- 以溴处理生成3-溴-1,10-邻菲咯啉和3,8-二溴-1,10-邻菲咯啉。
- 与异亚硝基噻唑基苯并噻唑基溴苯辛(isonitrosothiazolylbenzothiazolylmethanide)反应生成菲咯啉铜配合物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
The Phenomenon of Intramolecular Attractive S-O Interactions: Synthesis and Structure of (1, 10-Phenanthroline) copper (II) Complexes with Isonitroso-(4-methylthiazol-2-yl) acetamide and Isonitroso-(4-methylthiazol-2-yl)-(benzothiazol-2-yl) methanide
Domasevitch KV, et al.
Zeitschrift fur Naturforschung B, 52(3), 323-330 (1997)
Simple one-step synthesis of 3-bromo-and 3, 8-dibromo-1, 10-phenanthroline: fundamental building blocks in the design of metal chelates
Tzalis D, et al.
Tetrahedron Letters, 36(20), 3489-3490 (1995)
Novel oral phosphate binder with nanocrystalline maghemite-phosphate binding capacity and pH effect.
T M-H Nguyen et al.
International journal of pharmaceutics, 482(1-2), 21-26 (2014-12-03)
Hyperphosphatemia is one of the main risk factors contributing to morbidity and mortality in patients with end stage renal disease. The demand for a new phosphate binder is continuously increasing since the number of patients suffering under hyperphosphatemia is growing.
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