77386
2-溴-1-乙基吡啶四氟硼酸盐
≥97.0% (T)
别名:
BEP
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关于此项目
经验公式（希尔记法）:
C7H9BBrF4N
化学文摘社编号:
分子量:
273.86
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-900-2
Beilstein/REAXYS Number:
4059265
MDL number:
InChI key
YJDXVQLBIAJTHP-UHFFFAOYSA-N
InChI
1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1
SMILES string
F[B-](F)(F)F.CC[n+]1ccccc1Br
assay
≥97.0% (T)
form
crystals
reaction suitability
reaction type: Coupling Reactions
mp
103-107 °C
application(s)
peptide synthesis
functional group
bromo
Quality Level
General description
2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.
Application
2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:
- The synthesis of N-methylated peptides in solution and solid phase.
- The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.
Other Notes
用于肽合成的偶联试剂；与其他试剂如 BOP、PyBrOP、PyClU、BTFFH、CMBI 相比，外消旋作用更低、反应更快
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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Li P and Xu J
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Previous studies have shown that Zika virus can infect and be transmitted by A. albopictus. The World Health organization (WHO) has raised concerns of autochthonous transmission of the virus in regions where the vector is endemic. The aim of this
2?Bromo?1?ethyl Pyridinium Tetrafluoroborate (BEP)
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2003)
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