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Merck
CN

769800

Sigma-Aldrich

Resomer® RG 753 S,聚(D,L-丙交酯-co-乙交酯)

ester terminated, Lactide: Glycolide 75:25, lactide:glycolide 75:25

别名:

树脂® RG 753 S, PLGA

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About This Item

线性分子式:
HO[C2H4O2]n[C2H2O2]mCH3
CAS号:
UNSPSC代码:
12162002
NACRES:
NA.23

质量水平

形式

amorphous

投料比

lactide:glycolide 75:25

粘度

0.32-0.44 dL/g

转变温度

Tg 44-50 °C

储存温度

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

应用

Resomer® RG 753 S, 聚(D,L-丙交酯--乙交酯)是可生物降解、具有生物相容性的脂肪族聚酯,可用于开发纳米颗粒和微粒。 它是药物聚合物,在药物输送和基因传递方面具有应用潜力。能形成三维多孔支架,可用于组织工程。

法律信息

RESOMER is a registered trademark of Evonik Rohm GmbH

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Nanoparticles made of fluorescence-labelled poly (L-lactide-co-glycolide): preparation, stability, and biocompatibility
Weiss B, et al.
Journal of Nanoscience and Nanotechnology, 6(9-10), 3048-3056 (2006)
Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 125(3), 193-209 (2008)
Development and evaluation of novel biodegradable microspheres based on poly (d, l-lactide-co-glycolide) and poly (varepsilon-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: in vitro and in vivo studies
Mundargi RC, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 119(1), 59-68 (2007)
In vitro degradation of three-dimensional porous poly (D, L-lactide-co-glycolide) scaffolds for tissue engineering
Wu L and Ding J
Biomaterials, 25(27), 5821-5830 (2004)

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