推荐产品
质量水平
方案
97%
表单
liquid
反应适用性
reagent type: cross-linking reagent
折射率
n20/D 1.481
密度
1.098 g/mL at 25 °C
SMILES字符串
OCCOCCOCCOCCS
InChI
1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2
InChI key
GKKYNULPAQDGHI-UHFFFAOYSA-N
应用
2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.
- Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
- PEG-disulfide formation
- ultra-thin protein-resistant monolayers
- Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Skin Corr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Thiol-functionalized undecagold clusters by ligand exchange: Synthesis, mechanism, and properties.
Woehrle GH & Hutchison JE
Inorganic Chemistry, 44(18), 6149-6158 (2005)
Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor
Diehl KL, et al.
Nature Chemistry, 8(10) (2016)
Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology: glycan-dependent gp120/protein interactions.
Adams EW, et al.
Chemistry & Biology, 11(6), 875-881 (2004)
Thiol functionalized oligo-ethylene glycol, for modification of peptides/small molecules containing thiols or maleimide functional groups
Journal of Materials Chemistry, 9, 1121-1121 (1999)
Influence of surface functionalization and particle size on the aggregation kinetics of engineered nanoparticles.
Liu J, et al.
Chemosphere, 87(8), 918-924 (2012)
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