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质量水平
方案
95%
表单
liquid
折射率
n20/D 1.465
密度
1.039 g/mL at 25 °C
储存温度
−20°C
SMILES字符串
CC(C)N(C(C)C)P(OCCC#N)OCCC#N
InChI
1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3
InChI key
LDHWBEHZLFDXCU-UHFFFAOYSA-N
一般描述
Useful phosphorylating reagent used in oligonucleotide synthesis for adding a terminal phosphate group to the 3′ or 5′ hydroxyl.
应用
Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite may be used as a phosphitylating agent during the multi-step synthesis of (-)-1L-chiro-inositol 2,3,5-trisphosphate starting from L-quebrachitol.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
165.0 °F
闪点(°C)
73.9 °C
Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.
Francois JC, et al.
Proceedings of the National Academy of Sciences of the USA, 86(24), 9702-9706 (1989)
Synthesis from quebrachitol of 1L-chiro-inositol 2, 3, 5-trisphosphate, an inhibitor of the enzymes of 1D-myo-inositol 1, 4, 5-trisphosphate metabolism.
Liu C, et al.
Carbohydrate Research, 234, 107-115 (1992)
Seigo Nagata et al.
Nucleic acids research, 38(21), 7845-7857 (2010-07-28)
Though medicines that target mRNA are under active investigation, there has been little or no effort to develop mRNA itself as a medicine. Here, we report the synthesis of a 130-nt mRNA sequence encoding a 33-amino-acid peptide that includes the
Solid-phase synthesis of a New Diphosphate 5-Aminoimidazole-4-carboxamide Riboside (AICAR) derivative and studies toward cyclic AICAR diphosphate ribose.
D?Errico S, et al.
Molecules (Basel), 16(9), 8110-8118 (2011)
Inhibition of glutamate carboxypeptidase by phosphoryl and thiophosphoryl derivatives of glutamic and 2-hydroxyglutaric acid.
Lu H, et al.
Phosph. Sulfur Relat. Elem., 178(1), 17-32 (2003)
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