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Merck
CN

765430

Sigma-Aldrich

官能化金纳米粒子COOH

5 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

别名:

Au NP COOH, 金胶体

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About This Item

UNSPSC代码:
12162002
NACRES:
NA.23

物料

PEG 3000

质量水平

形式

dispersion in H2O
nanoparticles

包装

poly bottle of 1 mL

OD

50

直径

5 nm

pH值(酸碱度)

6.0-8.0 (25 °C)

溶解性

water: miscible

密度

1.00 g/cm3

λmax

515 nm

官能团

carboxylic acid

储存温度

2-8°C

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一般描述

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

应用

Carboxylic acid functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
功能化颗粒已被广泛用于研究纳米颗粒的细胞摄取和靶向药物递送

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 6, 2071-2071 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)

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