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Merck
CN

765260

Sigma-Aldrich

NH2 功能化金纳米颗粒

5 nm diameter, amine functionalized, PEG 3000 coated, OD 50, dispersion in H2O

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别名:
Au NP NH2, 金胶体
UNSPSC代码:
12162002
NACRES:
NA.23

物料

PEG 3000

质量水平

形式

dispersion in H2O
nanoparticles

包装

glass bottle of 1 mL

OD

50

直径

5 nm

pH值(酸碱度)

6.0-8.0 (25 °C)

溶解性

water: miscible

密度

1.00 g/cm3

λmax

515 nm

官能团

amine

储存温度

2-8°C

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应用

功能化颗粒已广泛用于研究纳米颗粒的细胞摄取和靶向药物递送。
Amine functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be used in the activation of silica nanosphere for the decomposition of formic acid. They may be used in the radiosensitization and imaging of cancer cells.
AuNPs can be potentially immobilized on antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. They can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization, which can be used in the diagnosis of COVID-19.

特点和优势

  • Negatively charged siRNA-PEG complex which is attached to positively charged GNPs is easily cleavable in reductive cytosolic environment thus enabling the release of siRNA into cytosol.
  • Decreases the cytotoxicity and increases efficiency of GNPs. PEG increases the stability of the nanoparticles and prevents agglomeration.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Gold nanoparticles for radiosensitizing and imaging of cancer cells
Borran AA, et al.
Radiation Physics and Chemistry, 152(25), 137-144 (2018)
Strong metal-molecular support interaction (SMMSI): amine-functionalized gold nanoparticles encapsulated in silica nanospheres highly active for catalytic decomposition of formic acid
Yadav M, et al.
Journal of Materials Chemistry, 22(25), 12582-12586 (2012)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 152(25), 1-4 (2020)
Scott H Brewer et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9303-9307 (2005-09-21)
The interaction of bovine serum albumin (BSA) with gold colloids and surfaces was studied using zeta-potential and quartz crystal microbalance (QCM) measurements, respectively, to determine the surface charge and coverage. The combination of these two measurements suggests that BSA binding
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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