跳转至内容
Merck
CN
所有图片(1)

文件

764825

Sigma-Aldrich

聚(乙二醇)甲醚-嵌段-聚（丙交酯-共-乙交酯）

PEG Mn 2,000, PLGA Mn 4,500

别名:

PEG-PLGA, mPEG-b-PLGA

登录查看公司和协议定价
所有图片(1)

About This Item

线性分子式:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
UNSPSC代码:
12162002
NACRES:
NA.23

形式

pellets

质量水平

100

投料比

lactide:glycolide 65:35

分子量

PEG Mn 2,000
PLGA Mn 4,500
average Mn 6,500 (total)

降解时间线

1-4 weeks

转变温度

Tm 241-246 °C

PDI

≤2.0

储存温度

2-8°C

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

两亲性嵌段共聚物 (AmBC) 由两种化学结构不同的均聚物嵌段组成。其中一个是亲水性的，另一个是疏水性的。这些大分子在水性介质中溶解时具有自组装的属性。PEG-PLGA 是一种最常用的可生物降解的两亲性嵌段共聚物，用于药物输送。PEG 是亲水性部分，PLGA 是疏水性部分。

应用

形成“隐形”聚乙二醇化微粒
用于合成用于药物差异递送和控释的靶向纳米粒子。

特点和优势

  • 生物相容性好，免疫原性低，可降解性好。
  • 通过改变嵌段共聚物链段大小以适应特定的应用，可以很容易地调节性质。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Thermosensitive self-assembling block copolymers as drug delivery systems.
Bonacucina, G., Cespi, M., Mencarelli, G., Giorgioni, G., & Palmieri, G. F.
Polymer, 3(2), 779-811 (2011)
PLGA-PEG Encapsulated sitamaquine nanoparticles drug delivery system against Leishmania donovani
Kumara, R., Sahoo, G. C., Pandeya, K., Dasa, V. N. R., Yousuf, M., Ansaria, S. R., & Dasa, P.
Journal of Scientific and Innovative Research, 3(1), 85-90 (2014)
Frank Gu et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(7), 2586-2591 (2008-02-15)
There has been progressively heightened interest in the development of targeted nanoparticles (NPs) for differential delivery and controlled release of drugs. Despite nearly three decades of research, approaches to reproducibly formulate targeted NPs with the optimal biophysicochemical properties have remained

商品

Solubility Enhancement of Hydrophobic Drugs

Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门