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Merck
CN

764213

Sigma-Aldrich

生物素-PEG4-炔

for copper catalyzed click labeling

别名:

乙炔-PEG4-生物素结合物

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About This Item

经验公式(希尔记法):
C21H35N3O6S
分子量:
457.58
MDL编号:
UNSPSC代码:
12161502
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

95%

表单

solid

反应适用性

reaction type: click chemistry

mp

55-64 °C

储存温度

−20°C

SMILES字符串

O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O

InChI

1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1

InChI key

SKMJWNZZFUDLKQ-QWFCFKBJSA-N

应用

生物素-PEG4-炔可以通过生物正交叠氮-炔加成反应对 4-叠氮苯丙氨酸 (AzPhe) 丝素蛋白进行改性,以制备光敏性蛋白质材料。
生物素化试剂,采用铜催化的 1,3 偶极环加成点击化学标记含炔烃的分子或生物分子。炔烃基团与叠氮化物反应形成稳定的三唑键,有助于将生物素引入目标炔烃改性体系。

凭借Synple 全自动合成平台(SYNPLE-SC002)自动标记您的生物素

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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