762342
三（3-羟丙基三氮基甲基）胺
95%, solid
别名:
3,3′,3′′-(4,4′,4′′-(次氨基三(亚甲基))三(1H-1,2,3-三唑-4,1-取代))三(正丁醇), THPTA
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关于此项目
经验公式（希尔记法）:
C18H30N10O3
化学文摘社编号:
分子量:
434.50
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.22
MDL number:
产品名称
三（3-羟丙基三氮基甲基）胺, 95%
SMILES string
OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1
InChI
1S/C18H30N10O3/c29-7-1-4-26-13-16(19-22-26)10-25(11-17-14-27(23-20-17)5-2-8-30)12-18-15-28(24-21-18)6-3-9-31/h13-15,29-31H,1-12H2
InChI key
VAKXPQHQQNOUEZ-UHFFFAOYSA-N
assay
95%
form
solid
mp
331-336 °C (decomposition)
storage temp.
2-8°C
Quality Level
reaction suitability
reagent type: ligand
reaction type: click chemistry
Application
三(3-羟丙基三氮基甲基)胺是一种水溶性铜(I)稳定配体，主要用于铜(I)催化烷基叠氮环加成(CuAAC)反应。
铜催化叠氮烷基环加成(CuAAC)的有效配体。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Patrik Fladischer et al.
Biotechnology journal, 14(3), e1800125-e1800125 (2018-06-05)
The site-specific incorporation of non-canonical amino acids (ncAAs) at amber codons requires an aminoacyl-tRNA synthetase and a cognate amber suppressor tRNA (tRNACUA ). The archaeal tyrosyl-tRNA synthetase from Methanocaldococcus jannaschii and the pyrrolysyl-tRNA synthetase (PylRS) from Methanosarcina mazei have been
Sheng Wang et al.
The Journal of pathology, 243(1), 78-88 (2017-06-29)
Protein modification by O-linked β-N-acetylglucosamine (O-GlcNAc) is emerging as an important factor in the pathogenesis of sporadic Alzheimer's disease (AD); however, detailed molecular characterization of this important protein post-translational modification at the proteome level has been highly challenging, owing to
A two-component'double-click'approach to peptide stapling.
Lau YH, et al.
Nature Protocols, 10(4), 585-585 (2015)
Vu Hong et al.
Bioconjugate chemistry, 21(10), 1912-1916 (2010-10-05)
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, optimized for biological molecules in aqueous buffers, has been shown to rapidly label mammalian cells in culture with no loss in cell viability. Metabolic uptake and display of the azide derivative of N-acetylmannosamine developed
Ofer Stempler et al.
Nature communications, 8(1), 315-315 (2017-08-23)
Bacteria have developed various mechanisms by which they sense, interact, and kill other bacteria, in an attempt to outcompete one another and survive. Here we show that Bacillus subtilis can kill and prey on Bacillus megaterium. We find that Bacillus
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