所有图片(1)
About This Item
经验公式（希尔记法）:
C25H21N3O4
分子量:
427.45
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.22
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![(1R,8S,9s)-双环[6.1.0]壬-4-炔-9-基甲基 N-琥珀酰亚胺碳酸酯 for Copper-free Click Chemistry](/deepweb/assets/sigmaaldrich/product/structures/969/022/d6776082-2f7a-47c7-bcd4-3830dac0fb7d/640/d6776082-2f7a-47c7-bcd4-3830dac0fb7d.png)
质量水平
表单
solid
反应适用性
reaction type: click chemistry
reagent type: cross-linking reagent
官能团
maleimide
储存温度
−20°C
SMILES字符串
O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O
InChI
1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
InChI key
NHFQNAGPXIVKND-UHFFFAOYSA-N
应用
马来酰亚胺功能化环辛炔衍生物，用于将环辛炔基团掺入含巯基化合物或生物分子。环辛烯在促进无铜叠氮炔环加成反应中是有用的。这种二苯并环辛炔将与叠氮官能化化合物或生物分子反应，而不需要 Cu (I) 催化剂产生稳定的三唑键。
应用包括：
应用包括：
- 蛋白-肽结合物
- 抗体酶或抗体-药物偶联物
- 蛋白或肽-寡核苷酸结合物
- 表面改性
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商品
无铜点击化学是点击化学的一种替代方法，可在较低的活化屏障下进行，且没有细胞毒性过渡金属催化剂。
Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.
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