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759902

Sigma-Aldrich

Dibenzocyclooctyne-PEG4-acid

for Copper-free Click Chemistry

别名:

Polyethylene glycol, DBCO-PEG4-Acid

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0.5 MG
CN¥4,968.26

CN¥4,968.26

国内现货，预计发货时间April 17, 2025详情

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0.5 MG
CN¥4,968.26

About This Item

经验公式（希尔记法）:
C32H40N2O8
分子量:
580.67
MDL编号:
MFCD22380749
UNSPSC代码:
12352106
PubChem化学物质编号:
329766822
NACRES:
NA.22

CN¥4,968.26

国内现货，预计发货时间April 17, 2025详情

获取大包装报价

表单

solid

反应适用性

reaction type: click chemistry
reagent type: linker

官能团

carboxylic acid

储存温度

−20°C

SMILES字符串

O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

InChI

1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)

InChI key

RMYANOWYMFCGGS-UHFFFAOYSA-N

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Aldrich® AtmosBag four-hand, non-sterile, size L, closure type, Zipper-lock

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Aldrich® AtmosBag two-hand, non-sterile, size micro, closure type, Zipper-lock

Z564397

Aldrich® AtmosBag

Aldrich® AtmosBag two-hand, non-sterile, size L, closure type, Zipper-lock

Z530220

Aldrich® AtmosBag

Aldrich® AtmosBag four-hand, non-sterile, size L, closure type, Tape-seal

Z108405

Aldrich® AtmosBag

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

feature

closure type Zipper-lock

feature

closure type Zipper-lock

feature

closure type Zipper-lock

feature

closure type Tape-seal

W × L × H

45 in. × 58 in. × 25 in., average inflated dimensions

W × L × H

23 in. × 38 in. × 11 in., average inflated dimensions

W × L × H

51 in. × 58 in. × 25 in., average inflated dimensions

W × L × H

45 in. × 58 in. × 25 in., average inflated dimensions

W × L

48 in. × 60 in. , deflated dimensions

W × L

23 in. × 43 in. , deflated dimensions

W × L

51 in. × 58 in. , deflated dimensions

W × L

45 × 57 , deflated dimensions

gas volume

500 L

gas volume

1.5 ft3

gas volume

520 L

gas volume

500 L

应用

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.
Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions. [1]

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    MKCW8608
    MKCT5033
    MKCP4389
    MKCL3200
    MKCD8909

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    Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi?Target Imaging
    Karver MR, et al.
    Angewandte Chemie (International Edition in English), 51(4), 920-922 (2012)
    Jianwen Xu et al.
    Chemistry, an Asian journal, 6(10), 2730-2737 (2011-09-29)
    Strategies to encapsulate cells in cytocompatible three-dimensional hydrogels with tunable mechanical properties and degradability without harmful gelling conditions are highly desired for regenerative medicine applications. Here we reported a method for preparing poly(ethylene glycol)-co-polycarbonate hydrogels through copper-free, strain-promoted azide-alkyne cycloaddition
    A Versatile Monomer for Preparing Well-Defined Functional Polycarbonates and Poly(estercarbonates)
    Xu J.; et al.
    Macromolecules, 44, 2260-2267 (2011)
    Selvanathan Arumugam et al.
    Bioorganic & medicinal chemistry letters, 21(23), 6987-6991 (2011-10-26)
    N-Terminally azido-modified peptides were labeled with the novel prosthetic labeling synthon [(18)F]azadibenzocyclooctyne ([(18)F]ADIBO) using copper-free azide-alkyne [3+2]-dipolar cycloaddition in high radiochemical yields (RCYs). (18)F-Labeled [(18)F]ADIBO was prepared by nucleophilic substitution of the corresponding tosylate in 21% overall RCY (EOB) in
    Strain-promoted copper-free "click" chemistry for 18F radiolabeling of bombesin.
    Lachlan S Campbell-Verduyn et al.
    Angewandte Chemie (International ed. in English), 50(47), 11117-11120 (2011-10-01)
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