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质量水平
同位素纯度
99.8 atom % D
表单
liquid
技术
HPLC: suitable
bio NMR: suitable
protein expression: suitable
沸点
101.4 °C (lit.)
mp
3.8 °C (lit.)
密度
1.107 g/mL at 25 °C
应用
pharmaceutical
储存温度
room temp
SMILES字符串
[2H]O[2H]
InChI
1S/H2O/h1H2/i/hD2
InChI key
XLYOFNOQVPJJNP-ZSJDYOACSA-N
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一般描述
氧化氘（D2O）也称为重水。它是水的氘化形式, H2O 中的两个质子被氘同位素所取代。
应用
D2O 可用作以下应用中的溶剂：
D2O 可通过H-D交换反应制备氘标记化合物，用于制药、生物分析、生物、环境化学等领域，可使用合适的分析方法研究药物代谢机制、反应机制、生物分子结构、食品残留农药等。.
- 高分辨率NMR（核磁共振）
- FTIR （傅里叶变换红外）
- 生物核磁共振研究
- 极化可见光拉曼光谱研究
- 蛋白质表达
D2O 可通过H-D交换反应制备氘标记化合物，用于制药、生物分析、生物、环境化学等领域，可使用合适的分析方法研究药物代谢机制、反应机制、生物分子结构、食品残留农药等。.
包装
该产品可以大包装形式供货，也可按需进行包装。 如需关于价格、供货形式及包装的信息，请联系稳定同位素客户服务。
储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
R Schweitzer-Stenner et al.
Journal of the American Chemical Society, 123(39), 9628-9633 (2001-09-27)
We have measured the polarized visible Raman and FTIR spectra of trialanine and triglycine in D(2)O at acid, neutral, and alkaline pD. From the Raman spectra we obtained the isotropic and the anisotropic scattering. A self-consistent spectral analysis of the
Raphael Böhm et al.
Structure (London, England : 1993), 28(2), 206-214 (2019-12-22)
The voltage-dependent anion channel (VDAC) forms the primary diffusion pore of the outer mitochondrial membrane. In its apo form, VDAC adopts an open conformation with high conductance. States of lower conductance can be induced by ligand binding or the application
Lars Holm et al.
American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)
A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body
Takhar Kasumov et al.
American journal of physiology. Heart and circulatory physiology, 304(9), H1201-H1214 (2013-03-05)
Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated
Frank Grüne et al.
Anesthesiology, 120(2), 335-342 (2013-09-07)
Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair cerebral aerobic metabolism in
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蛋白质结构分析有助于发现对治疗至关重要的疾病生物标志物和药物靶点。
Protein structure analysis aids in identifying disease biomarkers and drug targets crucial for therapeutic treatments.
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