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Merck
CN

75490

Sigma-Aldrich

DL -鸟氨酸 单盐酸盐

≥99.0% (AT)

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别名:
(±)-2,5-二氨基戊酸 单盐酸盐
线性分子式:
NH2(CH2)3CH(CO2H)(NH2) · HCl
CAS号:
分子量:
168.62
Beilstein:
4153338
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥99.0% (AT)

形式

powder

反应适用性

reaction type: solution phase peptide synthesis

mp

~233 °C (dec.)

应用

peptide synthesis

SMILES字符串

Cl.NCCCC(N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

InChI key

GGTYBZJRPHEQDG-UHFFFAOYSA-N

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应用

DL-Ornithine monohydrochloride may be used as a starting material in the synthesis of (-)-(1-2H)putrescine dihydrochloride via enzymatic decarboxylation.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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The Stereochemistry of the Enzymic Decarboxylation of l-Arginine and of l-Ornithine
Richards JC and Spenser ID
Canadian Journal of Chemistry, 60(22), 2810-2820 (1982)
Juan C Marini et al.
American journal of physiology. Endocrinology and metabolism, 303(11), E1348-E1353 (2012-10-18)
Citrulline is an amino acid synthesized in the gut and utilized for the synthesis of the conditionally essential amino acid arginine. Recently, the origin of the ornithine utilized for citrulline synthesis has become a matter of discussion. Multiple physiological factors
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
Irene Tsiapa et al.
Nuclear medicine and biology, 40(2), 262-272 (2012-12-15)
Radiolabeled RGD peptides that specifically target integrin α(ν)β(3) have great potential in early tumor detection through noninvasive monitoring of tumor angiogenesis. Based on previous findings of our group on radiopeptides containing positively charged aminoacids, we developed a new cyclic cRGDfK

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