形式
liquid
质量水平
浓度
0.5 M in THF
密度
0.896 g/mL at 25 °C
储存温度
2-8°C
SMILES字符串
CP(C)(C)=CC#N
InChI
1S/C5H10NP/c1-7(2,3)5-4-6/h5H,1-3H3
InChI key
KJFJIEHJCVSAKJ-UHFFFAOYSA-N
一般描述
(三甲基膦酰亚胺)乙腈是一种试剂,通常用于酯、N-Boc内酰胺、内酯和酰亚胺等具有较低反应性羧酸化合物通过Wittig烯烃化反应得到α,β-不饱和腈。它还可作为Mitsonobu反应的替代试剂,通过取代DEAD/PPh3以进行C-H和N-H键的烷基化反应。
其他说明
如果观察到沉淀,请略微加热使其溶解
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
靶器官
Respiratory system
补充剂危害
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
法规信息
危险化学品
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Tetrahedron Letters, 41(2), 235-237 (2000)
Cyanomethylenetrimethylphosphorane
e-EROS Encyclopedia of Reagents for Organic Synthesis (2003)
Cyanomethylenetrimethylphosphorane
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2003)
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