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Merck
CN

745774

Sigma-Aldrich

8-Amino-1-octanethiol hydrochloride

95%

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别名:
8-Mercaptooctylamine hydrochloride
经验公式(希尔记法):
C8H19NS · HCl
分子量:
197.77
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.23

质量水平

检测方案

95%

形式

solid

mp

158-163 °C

储存温度

2-8°C

SMILES字符串

SCCCCCCCCN.Cl

InChI

1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H

InChI key

CCWZBRKMJBSNQS-UHFFFAOYSA-N

一般描述

8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.

应用

8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.
Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption

象形图

Environment

警示用语:

Warning

危险声明

预防措施声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Photooxidation of amine-terminated self-assembled monolayers on gold
Lee S, et al.
The Journal of Physical Chemistry C, 114(23), 10512-10519 (2010)
Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging
Mori T, et al.
Analytical Biochemistry, 375(2), 223-231 (2008)
Trace analysis of an oligonucleotide with a specific sequence using PNA-based ion-channel sensors
Aoki H and Umezawa Y
Analyst, 128(6), 681-685 (2003)
Tuning the surface potential of gold substrates arbitrarily with self-assembled monolayers with mixed functional groups
Lin W, et al.
Physical Chemistry Chemical Physics, 11(29), 6199-6204 (2009)
Tillmann Utesch et al.
Langmuir : the ACS journal of surfaces and colloids, 28(13), 5761-5769 (2012-03-06)
Sulfite oxidase (SO) is an enzyme catalyzing the terminal step of the metabolism of sulfur-containing amino acids that is essential for almost all living organisms. The catalytic activity of SO in vertebrates strongly depends on the efficiency of the intramolecular

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