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74104

Sigma-Aldrich

4-(4,6-二甲氧基三嗪-2-基)-4-甲基吗啉盐酸盐

≥97.0% (calc. on dry substance, AT), for peptide synthesis

别名:

DMTMM, MMTM

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¥1,810.17
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¥5,689.21

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100 MG
¥1,810.17
500 MG
¥5,689.21

About This Item

经验公式（希尔记法）:
C10H17ClN4O3
CAS号:
3945-69-5
分子量:
276.72
Beilstein:
8026872
MDL编号:
MFCD03613550
UNSPSC代码:
12352005
PubChem化学物质编号:
57652501
NACRES:
NA.22

¥1,810.17

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产品名称

4-(4,6-二甲氧基三嗪-2-基)-4-甲基吗啉盐酸盐, 95% (HPLC)

质量水平

100

方案

95% (HPLC)

表单

powder

反应适用性

reaction type: Coupling Reactions

杂质

≤17 wt. % water

应用

peptide synthesis

官能团

ether

储存温度

−20°C

SMILES字符串

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

相关类别

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1 of 4

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606308T1502398136
Ethanolamine hydrochloride ≥99.0%

E6133

Ethanolamine hydrochloride

Ethanolamine-13C2 hydrochloride 99 atom % 13C, 99% (CP)

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Ethanolamine-13C2 hydrochloride

Triethanolamine hydrochloride ≥99.5% (titration)

T1502

Triethanolamine hydrochloride

Ethanolamine ACS reagent, ≥99.0%

398136

Ethanolamine

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

-

assay

≥99.0%

assay

99% (CP)

assay

≥99.5% (titration)

assay

≥99.0%

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

200

application(s)

general analytical
life science and biopharma
pharmaceutical

application(s)

-

application(s)

diagnostic assay manufacturing

application(s)

-

form

powder or crystals

form

solid

form

crystalline powder

form

liquid

solubility

water: 0.33 g/mL, clear, colorless to very faintly yellow

solubility

-

solubility

water: 0.333 g/mL, clear, colorless

solubility

water: miscible 1000 g/L at 20 °C

应用

4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉盐酸盐可用作以下转化反应的缩合剂：
  • 羧酸和胺在四氢呋喃中发生缩合反应，产生相应的酰胺。[1][2]
  • 羧酸与醇的酯化反应，产生相应的酯。[3]
  • 在质子溶剂中，将羧酸转化为相应的Weinreb酰胺。[4]

用作溶液和固相肽合成中的羧酸的活化剂；性能优于或相当于最畅销的偶联剂[5][6]

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302,H314

危险分类

Acute Tox. 4 Oral - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

198.5 °F - closed cup

闪点(°C)

92.5 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    BCCM7997
    BCCM1316
    BCCK3622
    BCCJ6584
    BCCH6420

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    如果您需要特殊版本，可通过批号或批次号查找具体证书。

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    Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).
    Kunishima M
    Synlett, 1999(08), 1255-1256 (1999)
    Chameen Samarawickrama et al.
    Cornea, 37(5), 609-616 (2017-11-28)
    To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations. A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These CLP-PEG hydrogels
    Synthesis and characterization of 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methylmorpholinium chloride.
    Kunishima M
    Tetrahedron Letters, 40(29), 5327-5330 (1999)
    M. Kunishima et al.
    Tetrahedron Letters, 40, 5327-5327 (1999)
    Vianney Delplace et al.
    Biomacromolecules, 21(6), 2421-2431 (2020-04-11)
    A hydrogel that can deliver both proteins and cells enables the local microenvironment of transplanted cells to be manipulated with a single injection. Toward this goal, we designed a hydrogel suitable for the co-delivery of neural stem cells and chondroitinase
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